Q about fertilization report
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Anonymous
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So ugh. Just got our fertilization report. Of 12 retrieved eggs, 9 mature and only 3 fertilized with PISCI. We’re dealing with age (40) and MFI.
Anyone know what, if anything, this means for Day 6? Should we just prepare for a bust or is there no relationship b/w poor fertilization and embryo development? We’re going to PGS should we actually have an embryo to test. |
Anonymous
I think that you should expect normal blast rates from the ones that fertilized (25-50%). Although with male factor you might be on the lower end of that, I’m not sure. Good luck! |
Anonymous
| Would your clinic consider freezing early (I assume you are planning an FET, not fresh transfer?)? I know opinions vary on this, but I'd consider it. We had one retrieval at 39 and several at 40, and each resulted in three fertilized. We didn't have male factor though, just DOR, so we only ever got three or four mature eggs. We always froze early hoping that they had the best chance of growing/surviving in utero. If you want to do genetic testing that won't work though. I think it would be hard if there was nothing to transfer, but hopefully that won't be the case for you. Wishing you the best! |
Anonymous
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Also dealt with similar issues. Ended up with 1 embryo. You start this process thinking you will get several embryos and you may end up with 0-2 and just have to move forward and hope for the best.
Our transfer of one was successful, but didn’t have an “optimal outcome”. Good Luck! |
Anonymous
| We had 13-9-3 and of those 3 one was PGS normal. He’s almost a year old now! |
Anonymous
| Hopefully you end up with a good lot to test. I am 38 and we had a round with only 3 eggs, 2 fertilized and one (according to them) very beautiful blast. We paid the PGS testing fee and but ended up deciding to go ahead with a fresh transfer because I didn't want to waste our only shot on PGS. That transfer ended in a second early loss, so I'm on to recurrent pregnancy loss panels...so possibly could have been normal but who knows. Just thought I'd offer the experience as another path to consider if you end up with 1. PGS is still considered experimental, so while I'm all for it to prioritize multiple blasts, I also wanted to recognize the possibility for a mosaic to self correct or a false negative given the lack of evidence on some of these PGS issues. |
Anonymous
| Any updates OP ? Hoping for the best. |
Anonymous
OP here. Just got the Day 6 call. All of the embryos shortly arrested after fertilization. Lab said the sperm was very poor quality even for PICSI. We’re told we need to use donor sperm or egg or both. Or donor embryo. It’s a bit much to process right now. But I think we’re done. Thanks to everyone who responded. |
Anonymous
I’m sorry this happened to you. I’d get another opinion somewhere else as egg quality, fertilization, and embryo development can depend heavily on the protocol. You might also want to look into a clinic that offers day 3 transfer. |
Anonymous
| Take MF seriously. Get a DNA fragmentation test and potentially consider TESE. I never had blasts until I used testicular sperm. I know everyone just does icsi with MF and says sperm doesn't matter, but it does. Believe me, I learned the hard way. |