PGS testing for donor eggs?

[Anonymous]

I consulted with two local fertility clinics about the donor egg process. First clinic doesn't think there is a need for PGS testing, given that I may only have about 3 embryos and that the donor is younger and healthier. The other clinic basically requires you to do PGS testing, no matter how many embryos we get. Just so confusing. PGS or not for donor eggs? What did you do, success, and what clinic? Thank you!

[Anonymous]

I did not do PGS. Got 3 blasts from. Cohort of 7 eggs. Blasts 1 and 2 have failed to implant.

It would have been cheaper to PGS the embryos if (and who really knows) they failed to implant bc they were abnormal.

Which clinic is requiring it? Odd.

[Anonymous]

Anonymous wrote:I did not do PGS. Got 3 blasts from. Cohort of 7 eggs. Blasts 1 and 2 have failed to implant.

It would have been cheaper to PGS the embryos if (and who really knows) they failed to implant bc they were abnormal.

Which clinic is requiring it? Odd.

Pp, are you the one I've been talking with on other forums about the DE process at GW? I'm so sorry to hear about the 2nd transfer.

I recently consulted with Dominion and was told that for their donor egg process, they only do PGS tested frozen embryo transfers.

[Anonymous]

Are there any sperm quality issues? My first DE transfer did not work but the second one took, no PGS. We used frozen eggs from a 26-year old donor.

[Anonymous]

Anonymous wrote:

Anonymous wrote:I did not do PGS. Got 3 blasts from. Cohort of 7 eggs. Blasts 1 and 2 have failed to implant.

It would have been cheaper to PGS the embryos if (and who really knows) they failed to implant bc they were abnormal.

Which clinic is requiring it? Odd.

Pp, are you the one I've been talking with on other forums about the DE process at GW? I'm so sorry to hear about the 2nd transfer.

I recently consulted with Dominion and was told that for their donor egg process, they only do PGS tested frozen embryo transfers.

Yes, that’s me. I’m pretty miserable after 2 failures, not sure what to do with the third embryo. That’s interesting about Dominion. I hadn’t heard that.

[Anonymous]

We are in the SGF 1:2 program -- out of 10 blasts, 6 were PGS normal. Donor is 28. Glad we tested.

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I did not do PGS. Got 3 blasts from. Cohort of 7 eggs. Blasts 1 and 2 have failed to implant.

It would have been cheaper to PGS the embryos if (and who really knows) they failed to implant bc they were abnormal.

Which clinic is requiring it? Odd.

Pp, are you the one I've been talking with on other forums about the DE process at GW? I'm so sorry to hear about the 2nd transfer.

I recently consulted with Dominion and was told that for their donor egg process, they only do PGS tested frozen embryo transfers.

Yes, that’s me. I’m pretty miserable after 2 failures, not sure what to do with the third embryo. That’s interesting about Dominion. I hadn’t heard that.

Have you had the WTF talk yet with Dr. F? Not that it would help with the frustration, but if he has suggested anything different for next steps.

[Anonymous]

PGS is great if u have plenty of embryos. Not as helpful if u have only a few. There is a risk to the embryo (small risk) and also a risk that an embryo that would have resulted in a healthy baby shows up as not normal (also small risk). Few REs will transfer abnormal embryos. I typically hear of it in non donor cycles. It feels crappy not knowing if it’s the embryo or something else if the transfer fails though. If u have many embryos, PGS helps point out those most likely to be successful so you’re less likely to have a failed transfer, and if u have more than you’ll use there’s no concern about the risks. Generally half of all embryos from donors aren’t normal. It’s hard to go though failed transfers from a donor cycle but also not at all surprising that some would fail without PGS testing.

[Anonymous]

one of our three donor egg embryos was abnormal. given that a miscarriage can waste about six months of your life in a very heartbreaking way, any chance to eliminate bad embryos is worthwhile in my book.

[Anonymous]

I'm a true believer in PGS since it showed all eggs/embryos I produced were abnormal saving me from multiple failed transfers and miscarriages. WE moved on to DE and testing all embryos, and have 5 normals. I'm set for transfer this month!

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:I did not do PGS. Got 3 blasts from. Cohort of 7 eggs. Blasts 1 and 2 have failed to implant.

It would have been cheaper to PGS the embryos if (and who really knows) they failed to implant bc they were abnormal.

Which clinic is requiring it? Odd.

Pp, are you the one I've been talking with on other forums about the DE process at GW? I'm so sorry to hear about the 2nd transfer.

I recently consulted with Dominion and was told that for their donor egg process, they only do PGS tested frozen embryo transfers.

Yes, that’s me. I’m pretty miserable after 2 failures, not sure what to do with the third embryo. That’s interesting about Dominion. I hadn’t heard that.

Have you had the WTF talk yet with Dr. F? Not that it would help with the frustration, but if he has suggested anything different for next steps.

We haven’t yet. I needed a couple weeks to take a mental break, but will schedule with him soon. I guess it’s true that the first 2 could have been abnormal but I also want to investigate my lining and transfer timing. With only one embryo left I can’t leave anything to chance.

[Anonymous]

Anonymous wrote:

Anonymous wrote:I did not do PGS. Got 3 blasts from. Cohort of 7 eggs. Blasts 1 and 2 have failed to implant.

It would have been cheaper to PGS the embryos if (and who really knows) they failed to implant bc they were abnormal.

Which clinic is requiring it? Odd.

Pp, are you the one I've been talking with on other forums about the DE process at GW? I'm so sorry to hear about the 2nd transfer.

I recently consulted with Dominion and was told that for their donor egg process, they only do PGS tested frozen embryo transfers.

I may be fuzzy on this but I think all PGS is on frozen embryos. You can't get the results back fast enough for fresh.

[Anonymous]

Anonymous wrote:I'm a true believer in PGS since it showed all eggs/embryos I produced were abnormal saving me from multiple failed transfers and miscarriages. WE moved on to DE and testing all embryos, and have 5 normals. I'm set for transfer this month!

Yay! It's an exciting time. Good luck!

[Anonymous]

Another reason to PGS test (in addition to avoiding failed transfers) is the cost of freezing embryos and future planning. If you have 5 embryos and the first is successful, you then pay to store the remaining for the foreseeable future. It adds up. If they are abnormal, you have just spent additional money for non-viqble embryos. Further, if you were counting on a sibling and assume you have a shot, you would be in for additional heartbreak.

[Anonymous]

We did PGS on our donor embryos. There were five total and 3 came back abnormal. The other two were inconclusive. We ended up transferring both the inconclusives and had two healthy babies.