Three miscarriages in a year and all my tests are normal. What next?

Anonymous
I'm starting down the road of a primary infertility diagnosis and feeling fairly freaked out.

I'm 34 and have had three miscarriages in the last year. I don't seem to have any trouble getting pregnant, but all were missed miscarriages at an 8 week scan. All my bloodwork came back normal (thyroid, diabetes, lupis etc) and our second miscarriage tested negative for any genetic abnormalities (still waiting on results from the third miscarriage). Assuming further testing doesn't turn up a uterine issue, my internet research suggests that I'm looking at a diagnosis of recurrent miscarriage with no known cause.

What other things can a fertility clinic tell me? Is IVF really an option if I don't have a genetic problem with my embryos and I get pregnant just fine without it? Most of the stories I know involve trouble actually conceiving and/or genetic issues. Would love to hear from anyone who has had a similar experience.
Anonymous
My doc told me to take a baby aspirin every day in case it was a blood clotting issue. Also progesterone suppositories as soon as you get a positive. I’m sorry and wish you luck.
Anonymous
PCOS? That’s what friends of mine dealt with.
Anonymous
Had the exact same experience. Miscarried in Nov, Feb, and July, all at around 6-7 weeks, then found out in October I was pregnant for the 4th time in the span of a year and pregnancy #4 stuck (baby born in June). I did get on progesterone right away after finding out I was pregnant so maybe that was the thing that helped. No diagnosed issues but just had blood tests done and no further testing. Fingers crossed that your body figures out that its supposed to keep the next little embryo in there to grow.
Anonymous
Re: blood types .. being + or - refers to the D antigen. Some of the women in our family had a problem with the presence/or lack of presence, of the E antigen. It can cause, and did for us, the same problem as a mismatch with the D antigen. It's rare that it causes a problem which is why Drs don't go looking for it. Just mentioning.
Anonymous
Anonymous wrote:I'm starting down the road of a primary infertility diagnosis and feeling fairly freaked out.

I'm 34 and have had three miscarriages in the last year. I don't seem to have any trouble getting pregnant, but all were missed miscarriages at an 8 week scan. All my bloodwork came back normal (thyroid, diabetes, lupis etc) and our second miscarriage tested negative for any genetic abnormalities (still waiting on results from the third miscarriage). Assuming further testing doesn't turn up a uterine issue, my internet research suggests that I'm looking at a diagnosis of recurrent miscarriage with no known cause.

What other things can a fertility clinic tell me? Is IVF really an option if I don't have a genetic problem with my embryos and I get pregnant just fine without it? Most of the stories I know involve trouble actually conceiving and/or genetic issues. Would love to hear from anyone who has had a similar experience.


Have you had other miscarriages before this year? How many kids do you already have?
Anonymous
Consider DNA fragmentation testing for your husband. High fragmentation can cause poor embryos in IVF and recurrent miscarriages.
Anonymous
OP here- I did use progesterone suppositories as soon as I got a BFP this third pregnancy. It was awful stuff for me!

I don't think I have PCOS as I've never had an abnormal pelvic and I have none of the symptoms. I assume that my Dr will make sure to completely rule it out now.

These are my only three pregnancies- PP who got pregnant on #4 you give me hope!
Anonymous
Anonymous wrote:My doc told me to take a baby aspirin every day in case it was a blood clotting issue. Also progesterone suppositories as soon as you get a positive. I’m sorry and wish you luck.


+1 Worked for me. Plus an acupuncturist for some extra woo medicine and lots of hand holding. I eliminated dairy, gluten, caffeine and alcohol under her direction. (gluten I had to have after I passed the 3m mark, sorry!)
Anonymous
I’ve had 3 miscarriages before my first child. I was 34. A dr back in Europe prescribed low dose naltrexone in case it was a autoimmune issue. Not sure if it helped at all but the fourth pregnancy went fine. I got pregnant with my second by surprise as soon as my cycle came back. Like you I seemed to be able to conceive really easily. Don’t worry too much about it.
Anonymous
You need to pursue immune testing.
Anonymous
Anonymous wrote:OP here- I did use progesterone suppositories as soon as I got a BFP this third pregnancy. It was awful stuff for me!

I don't think I have PCOS as I've never had an abnormal pelvic and I have none of the symptoms. I assume that my Dr will make sure to completely rule it out now.

These are my only three pregnancies- PP who got pregnant on #4 you give me hope!


Did you get tested for progesterone levels? I was on suppositories and my progesterone levels came back extremely low. Started PIO shots and levels went up and my pregnancy was essentially saved. Suppositories apparently weren’t doing anything for me.
Anonymous
Anonymous wrote:You need to pursue immune testing.


+1 and clotting. I also had 3 miscarriages in a year (after a normal successful pregnancy) and turned out to have both immune and clotting issues. With treatment for both, I carried my next pregnancy to term.

I saw Dr. Abbasi at CFA.
Anonymous
Anonymous wrote:My doc told me to take a baby aspirin every day in case it was a blood clotting issue. Also progesterone suppositories as soon as you get a positive. I’m sorry and wish you luck.


I highly recommend this. I have had 7 miscarriages and I have three kids now. I got pregnant with my daughter after my second round of ivf. We used aspirin and suppositories. I had four natural pregnancies subsequently. The two that stuck were the ones I used aspirin and progesterone. Good luck OP. ❤️
Anonymous
Anonymous wrote:
Anonymous wrote:You need to pursue immune testing.


+1 and clotting. I also had 3 miscarriages in a year (after a normal successful pregnancy) and turned out to have both immune and clotting issues. With treatment for both, I carried my next pregnancy to term.

I saw Dr. Abbasi at CFA.


I am PP and also used Dr. Abbasi after trying Shady Grove (6 unsuccessful IUIs with them). Highly recommend.
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