Husband travelling - should I ask my clinic if I can do suppositories instead of PIO?

Anonymous
For several reasons I have issues administering my PIO shot by myself. Has anyone ever been able to “skip” one day or two by substituting with vaginal Progesterone?
Anonymous
The nurses at your clinic may be willing to do it.
Anonymous
I have, but honestly, it's not so hard to inject yourself. Have your husband or a nurse Mark the spot with a sharpie or pen. Then look at yourself in a mirror and inject.
Anonymous
Anonymous wrote:I have, but honestly, it's not so hard to inject yourself. Have your husband or a nurse Mark the spot with a sharpie or pen. Then look at yourself in a mirror and inject.


This.

Or if you have a friend or family member who can administer, my neighbor would do mine since dh is too squeamish, then I got comfortable doing them myself.
Anonymous
I don't think capsules and injections are interchangeable. I had to do both.
Anonymous
It's not that bad!! I had to give myself a couple of injections and it hurt less than when my husband did it. I laid on my side in my bed and did it that way. I'm not very flexible, but I managed to do it without too much issue.
Anonymous
The injections are not hard to do yourself. I did all of mine myself during one cycle. That said, I had success with a cycle when I used the vaginal suppositories. You might ask your doctor if you can switch if that is something you are more comfortable with. Otherwise, just ride it out.
Anonymous
for those who did the shots yourself - did you have to inject in the thigh for easier reach?
Anonymous
I didn't, because my center said not to. I'm not sure if it was a real reason or this is how we do it reason.
Anonymous
Anonymous wrote:for those who did the shots yourself - did you have to inject in the thigh for easier reach?


I was told by a nurse that it's super painful. She said women who try it end up only doing it once.
Anonymous
I did my injections myself in this exact situation--DH was gone for 3 days. In my case I was already doing the shot preparation so that part was familiar, so I just told myself I had to do it and did it. There's nothing like knowing you have to get through something to help you get through it. Deep breaths, you'll feel great after for overcoming this fear. Also, I did my injections in the same spot my husband had been doing them, I used a mirror and sort of twisted around to reach.
Anonymous
I was looking at another thread and stumbled across this. UMM please stop with the agony of PIO. If you are getting PIO at Shady Grove then stop it. You are part of their PIO study and the results when it comes to live births are negligible. No need to suffer. You CAN request the suppositories and still get the same effect. If it's in the cards for you to have a pregnancy than you will. No need for extra suffering. And if you have a thyroid issue - DEFINITELY get off the PIO. Ask your regular Endo what they would think about putting sesame, olive, peanut or cottonseed oils into your muscle?!? Look it up. I'm not lying. I did the PIO thing, it caused a allergic response (like a really bad flu) and I lost both pregnancies. You got other options.
Anonymous
Anonymous wrote:I was looking at another thread and stumbled across this. UMM please stop with the agony of PIO. If you are getting PIO at Shady Grove then stop it. You are part of their PIO study and the results when it comes to live births are negligible. No need to suffer. You CAN request the suppositories and still get the same effect. If it's in the cards for you to have a pregnancy than you will. No need for extra suffering. And if you have a thyroid issue - DEFINITELY get off the PIO. Ask your regular Endo what they would think about putting sesame, olive, peanut or cottonseed oils into your muscle?!? Look it up. I'm not lying. I did the PIO thing, it caused a allergic response (like a really bad flu) and I lost both pregnancies. You got other options.

Very interesting and thanks. I do have subclinical thyroid and it’s ranged from 2.3 to as high as 4 when I was on stimms. I always thought it was the estrogen pills that made my thyroid worse not PIO. I am not part of the shady grove study but good to know. So sorry about the losses. If I may ask did you do another transfer with suppositories only?
Anonymous
To "subclinical thyroid and it’s ranged from 2.3 to as high as 4" - I learned the hard way that if your TSH is above 2.5 your chances of a successful embryo transfer are very low. Visit PubMed and look at the articles regarding TSH levels, fertility, IVF outcomes. There is quite a bit of debate among different RE's and regular Endocrinologists as to the effect of TSH & iodine levels affecting fertility. Do NOT let Doctors treat you by TSH alone. Your free T4 is a much better indicator of your overall thyroid effectiveness. (Visit "Stop the Thyroid Madness" website to see the newest protocols and research.) I left Shady Grove and went to another practice. The doctor at the other practice looked at my records and was not impressed. For him, he was like "why didn't they check this? Why did they put you on that? Why the eff did they do a transfer on that date with those numbers?!"

Please get your TPO antibodies tested in relation to your thyroid issue. If you are a Hashimoto's patient (test positive for the autoimmune disorder), you need to start thyroid treatment. Here's why, when your embryo implants and starts to grow, your thyroid hormones are the only thyroid hormones it has to rely on for the first 12 weeks of gestation. For some patients this can over-tax your body. If you aren't medicated properly (and monitored) your TSH will spike, your immune system will have a fit and you'll be sitting there crying after 4 weeks going "WTF?! I was pregnant last week!"

As for suppositories, I'm moving to non-DC area practice and then we'll go from there. I looked at all the CDC stats for all the clinics in the Metro DC area and unfortunately none of them perform up to national average for women over 35. NONE. Not Shady Grove, CCRM, Washington FTC, Dominion, none. The CDC and SART stats for the clinics around here are below national average. Screw that.

It sounds like you're still doing the injections for this round. Best advice, draw a fist sized circle in the right IM injection area. Ice that bullseye circle for 10 minutes (paper towel between you and the ice bag) the do the injection. It might not be that bad when you can't feel the poke.

Best of luck to you. GET that TSH down!!
Anonymous
Anonymous wrote:To "subclinical thyroid and it’s ranged from 2.3 to as high as 4" - I learned the hard way that if your TSH is above 2.5 your chances of a successful embryo transfer are very low. Visit PubMed and look at the articles regarding TSH levels, fertility, IVF outcomes. There is quite a bit of debate among different RE's and regular Endocrinologists as to the effect of TSH & iodine levels affecting fertility. Do NOT let Doctors treat you by TSH alone. Your free T4 is a much better indicator of your overall thyroid effectiveness. (Visit "Stop the Thyroid Madness" website to see the newest protocols and research.) I left Shady Grove and went to another practice. The doctor at the other practice looked at my records and was not impressed. For him, he was like "why didn't they check this? Why did they put you on that? Why the eff did they do a transfer on that date with those numbers?!"

Please get your TPO antibodies tested in relation to your thyroid issue. If you are a Hashimoto's patient (test positive for the autoimmune disorder), you need to start thyroid treatment. Here's why, when your embryo implants and starts to grow, your thyroid hormones are the only thyroid hormones it has to rely on for the first 12 weeks of gestation. For some patients this can over-tax your body. If you aren't medicated properly (and monitored) your TSH will spike, your immune system will have a fit and you'll be sitting there crying after 4 weeks going "WTF?! I was pregnant last week!"

As for suppositories, I'm moving to non-DC area practice and then we'll go from there. I looked at all the CDC stats for all the clinics in the Metro DC area and unfortunately none of them perform up to national average for women over 35. NONE. Not Shady Grove, CCRM, Washington FTC, Dominion, none. The CDC and SART stats for the clinics around here are below national average. Screw that.

It sounds like you're still doing the injections for this round. Best advice, draw a fist sized circle in the right IM injection area. Ice that bullseye circle for 10 minutes (paper towel between you and the ice bag) the do the injection. It might not be that bad when you can't feel the poke.

Best of luck to you. GET that TSH down!!


Thanks- what was your TSH when you did your transfers? Also to be clear you got two BFPs but miscarried because of the thyroid? Or was it BFNs because of thyroid?
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