Forgot last night’s progesterone

[Anonymous]

Hoping someone can reassure me.

I am 8 days post 5-day fresh transfer. I take a progesterone (Endometrin 100mg) vaginally twice per day. Woke up today to realize I forgot last night’s dose.

My beta is on Monday, which will be 11 days post-transfer. However, I’ve had a positive home pregnancy test result for 4 days now, with a darker line each day. Now I am worried I ruined everything with this missed dose. It’s been a long road to get here and I feel stupid.

Called my clinic and the nurse said that I can take an additional dose this afternoon if it would help me feel better, but she doesn’t think it’s necessary. She said it would probably be fine but wasn’t very reassuring.

Any insight?

[Anonymous]

Anonymous wrote:Hoping someone can reassure me.

I am 8 days post 5-day fresh transfer. I take a progesterone (Endometrin 100mg) vaginally twice per day. Woke up today to realize I forgot last night’s dose.

My beta is on Monday, which will be 11 days post-transfer. However, I’ve had a positive home pregnancy test result for 4 days now, with a darker line each day. Now I am worried I ruined everything with this missed dose. It’s been a long road to get here and I feel stupid.

Called my clinic and the nurse said that I can take an additional dose this afternoon if it would help me feel better, but she doesn’t think it’s necessary. She said it would probably be fine but wasn’t very reassuring.

Any insight?

Agree with the nurse. It won't make a difference way or the other. Some REs don't even use progesterone as the studies are mixed on whether it actually helps things along.

I know it's hard not to stress over every little thing during this process... hang in there, OP.

[Anonymous]

Anonymous wrote:

Anonymous wrote:Hoping someone can reassure me.

I am 8 days post 5-day fresh transfer. I take a progesterone (Endometrin 100mg) vaginally twice per day. Woke up today to realize I forgot last night’s dose.

My beta is on Monday, which will be 11 days post-transfer. However, I’ve had a positive home pregnancy test result for 4 days now, with a darker line each day. Now I am worried I ruined everything with this missed dose. It’s been a long road to get here and I feel stupid.

Called my clinic and the nurse said that I can take an additional dose this afternoon if it would help me feel better, but she doesn’t think it’s necessary. She said it would probably be fine but wasn’t very reassuring.

Any insight?

Agree with the nurse. It won't make a difference way or the other. Some REs don't even use progesterone as the studies are mixed on whether it actually helps things along.

I know it's hard not to stress over every little thing during this process... hang in there, OP.

Thank you for this. I didn’t know the studies were not conclusive re: progesterone’s usefulness. I figured they gave it to me for a good reason and I messed it up. Ugh, Monday cannot be here quickly enough...

-OP

[Anonymous]

I do not think you should read anything into your nurse not sounding “encouraging.” This is a stressful process for all patients. Your nurse probably wanted to sound as neutral as possible. FYI, two pills vaginally per day is not that much (i.e. it looks like minimal supplementation in addition to what your body produces). I had to take twice that PLUS intramuscular injections of PIO every other day.

Good luck!

[Anonymous]

Anonymous wrote:I do not think you should read anything into your nurse not sounding “encouraging.” This is a stressful process for all patients. Your nurse probably wanted to sound as neutral as possible. FYI, two pills vaginally per day is not that much (i.e. it looks like minimal supplementation in addition to what your body produces). I had to take twice that PLUS intramuscular injections of PIO every other day.

Good luck!

Thanks. Was your intramuscular progesterone for a fresh cycle? I know my clinic has you do those for frozen.

I can be pretty spacey about schedules so was proud that I hadn’t messed up my IVF protocol yet, so I think this just shook me up. Really hoping for the best. This is my first cycle.

-OP

[Anonymous]

Anonymous wrote:

Anonymous wrote:I do not think you should read anything into your nurse not sounding “encouraging.” This is a stressful process for all patients. Your nurse probably wanted to sound as neutral as possible. FYI, two pills vaginally per day is not that much (i.e. it looks like minimal supplementation in addition to what your body produces). I had to take twice that PLUS intramuscular injections of PIO every other day.

Good luck!

Thanks. Was your intramuscular progesterone for a fresh cycle? I know my clinic has you do those for frozen.

I can be pretty spacey about schedules so was proud that I hadn’t messed up my IVF protocol yet, so I think this just shook me up. Really hoping for the best. This is my first cycle.

-OP

I did not expect to be spacey on these things until i started IVF and quickly got overwhelmed by the changing routine. Estrace 2x a day for 4 days then up to 3x per day; lupron in the AM, progesterone at night, dont forget the vitamins. Now i go full 7-day pill container and i have alarms on my phone for meds. Otherwise i just screw it up!

[Anonymous]

Oh man the scheduling stress of ART is the worst, OP. Crossing my fingers that things work out for you this month!

[Anonymous]

I made a grid where I would literally have to check off each pill. It was annoying but it ensured I didn’t miss anything. No way I could have kept track of everything otherwise.

[Anonymous]

OP ... honestly I think a lot of the transfer prep is for ppl to think they did everything possible. I did 3 rounds and twice I forgot a pill and they were like don’t worry about it.

[Anonymous]

Anonymous wrote:

Anonymous wrote:I do not think you should read anything into your nurse not sounding “encouraging.” This is a stressful process for all patients. Your nurse probably wanted to sound as neutral as possible. FYI, two pills vaginally per day is not that much (i.e. it looks like minimal supplementation in addition to what your body produces). I had to take twice that PLUS intramuscular injections of PIO every other day.

Good luck!

Thanks. Was your intramuscular progesterone for a fresh cycle? I know my clinic has you do those for frozen.

I can be pretty spacey about schedules so was proud that I hadn’t messed up my IVF protocol yet, so I think this just shook me up. Really hoping for the best. This is my first cycle.

-OP

It was for a frozen embryo transfer. The protocol would have been pretty much the same for a fresh cycle because I had a fresh transfer tentatively planned following retrieval/fertilization depending on how many embryos would make it to blast (doctor suggested not to bother with PGS if say, only one or two made it to blast) and the protocol for such a fresh transfer would have been four pills a day and intramuscular injection every third day if I recall correctly. I ended up having just enough blasts for PGS to be worth it, so did frozen transfers. Upon doing the FET, my blood test suggested that I need more progesterone so they increased the frequency of the injections.

[Anonymous]

Think about all the women who get knocked up and don’t even know it- some giving birth and not knowing they were pregnant until then.

Clearly you’ll be fine. Congrats on the beta