re recommendation

[Ivfhelp]

Hi,
I need an re recommendation. I had dor and my first Ivf worked. After my pregnancy, my dor went away and i've failed 11 cycles (last two at Cornell with biochemicals). I'm unsure what to do now. I have bad embryo quality. I'm considering ccrm in Virginia or staying at Cornell. My embryos don't make it to blast so I'm not all the genetic testing will work for me. Local drs are out of ideas. Any recommendations?

[Anonymous]

I really like Dr. Payson at CCRM VA. He is candid while also being warm and reassuring. Good luck!

[Anonymous]

I'm a big fan of CCRM, but they believe strongly in Day 5 and 6 PGS testing. I asked about Day 3 transfers and they said if the embryo doesn't make it to Day 5 or 6 in their lab, it probably wouldn't have succeeded anyway.

Two ways to understand that: either a) their lab is so good, they may be able to get your embryos to blast where they haven't before or b) you'll never succeed at CCRM because your embryos need an earlier/Day 3 transfer.

If you believe A is true, CCRM (and frankly after 11 cycles, I'd go out to their CO facility). If you believe B is true, stick with Cornell.

Or investigate immune issues at SIRM NY. Or donor eggs.

Those would be my choices in your shoes.

[Anonymous]

Thanks. I tried day 5 and all my cycles were cancelled because nothing made it. What sirm do about Immune issues? What would make you a candidate? I've had 1 ivf pregnancy and two biochemicals (last two at Cornell).

[Anonymous]

I've only gotten less than 5 blasts over all my cycles (over 100 embryos) so hoping for a blast seems pointless.

[Anonymous]

If you're older, not sure you'd want to go down the hole of immune issues since age is the likely issue. If you're younger, it may be worth a look.

If you only did 2 cycles at Cornell and the other 9 were the more typical, high dose cycles, I'd stick with Cornell. (I'm assuming they used their low dose protocol.) Certainly no guarantee, but if you at least got chemicals at Cornell, you know that you got blasts.

You could also do a consult with CCRM. Historically, I think they had a significant advantage, but I don't think that they're so far ahead of others now. Certainly, they're still one of the best.

After 11 cycles, I'm sure people have talked to you about DE, too.

[Anonymous]

Not really. I'm still young so no one is pushing donor yet (one dr out here mentioned it given the history and said he would push it if i was older). About a third of my cycles have been high dose but most have been low dose. Thanks for all your help.

[Anonymous]

how does DOR go away? as you stated