Does PCOS affect egg quality?

[Anonymous]

My REs (from two different clinics) have never mentioned this but I heard it reacently. I always produce a lot of eggs on stimming and am wondering if the quality of them stinks.

[Anonymous]

Yes. Especially if you are insulin resistant. REs prescribe metformin to help with egg quality among other things. There are reports that CoQ10 is also helpful.

[Anonymous]

what is the correlation? Between pcos and quality?

[Anonymous]

At least in my case, yes. DD #1 was conceived via IUI. Dr. said he couldn't believe that I didn't have multiples bc there were so many follicles, and that the eggs must have been lousy quality. DD #2 was IVF. At the retrieval, they harvested 20 eggs, but only 7 fertilized. They implanted 1, which was DD #2, and there were 3 left to freeze. Dr. again commented that the numbers were brought down so much from 20 to basically 4 because eggs were not good quality.

[Anonymous]

Yes, this means that typically if the #'s go down by 50% at each stage pcos womens numbers go down by a lot more. My example-they retrieved over 50 follicles, 7 are frozen.

[Anonymous]

Yes pcos adversely affects eggs BUT because production is so high and the stims help pcos women tend to do remarkably well with ivf ESP if not obese

[Anonymous]

HUH, interesting, PPs. Not in my experience. I got pregnant on the first try after metformin both times -- both kids are very healthy.

I'd guess if you need more than metformin to control the PCOS maybe there are compounding factors?

[Anonymous]

Anonymous wrote:HUH, interesting, PPs. Not in my experience. I got pregnant on the first try after metformin both times -- both kids are very healthy.

I'd guess if you need more than metformin to control the PCOS maybe there are compounding factors?

PP, how much Met did you take?