HLA and KIR Testing

[Anonymous]

I have been reading the posts about immune issues/tests and have a question. Could someone please explain what HLA and KIR testing are? Are they genetic tests for the mother? I am using donor egg, so are these tests something that I should look into? Or would they only apply to OE? (Apologies if some of this info is out there on the web; I often find the "plain English" explanations of DCUMers more helpful.)

[Anonymous]

Here are few links to Dr Braverman's website on the topic

http://www.preventmiscarriage.com/Blog/2013/April/HLA-Haplotyping-A-Treasure-Chest-of-Information-.aspx
http://www.preventmiscarriage.com/Reproductive-Immunology/HLA-Genes/HLA-Matching.aspx
http://www.preventmiscarriage.com/Reproductive-Immunology/HLA-Genes.aspx


DE does not bypass the HLA issues. HLA issues exist between the protein in the sperm and the protein in the uterus.

[Anonymous]

KIR can point to implantation issues and that has nothing to do with the genetics of the embryo. PP listed some really good resources.