canceled cycles?

[Anonymous]

Hi all. I am the poster from the IUI to IVF thread. In the end, we canceled but not due to too many follicles. Instead, when my menopur dose was lowered my estrogen plummeted and we canceled for that reason. We are moving on to IVF and I was feeling okay about it until google. Google told me that plummeting estrogen is a sign of poor follicle quality. Now I'm feeling panicky. Has anyone had a canceled cycle for similar reasons and gone on to success? I feel like I need to wash away what I read with some good stories!

(My AMH was fine but my RE said follicle count and quality are not the same so I'm not that reassured.)

[Anonymous]

You know, I suspect that the reason it lowed was because the stims was lowered, which makes sense! Sounds like they just went overboard.

I also believe in an IVF cycle they don't lower the doses as time goes on, typically (Im only one person but in all three of my cycles, they started me on one dose and increased the dosage as time went on. That said, I am definitely a poor responder. The only time they didn't do this was for my third cycle, in which they started off with the max doses knowing that's what I would need, since they'd learned that in the previous two cycles. I suspect that's the only time you become a "we'll lower it if we need to" sort of person"). And, despite being a poor responder, 2/3 of those cycles worked.

Plus, the fact that you responded so well to the IUI meds (too well, it sounds like!) bodes well.

Plus, the fact that they have done a little tinkerign withyou now, which has real diagnostic value- they know what's too much for you, and it sounds like they know what's not enoguh as well (at least what's not enough onec you become overstimulated).

I know it's hard not to worry (BELIEVE ME) but this- to this non RE- actually seems like something you can cross of your list.

Good luck!

[Anonymous]

Also, it seems like something like 98% of what's on the Internet about anything to do with infertility is misinformed/inacurate/ is just someone's opinion and not based on any actual scientific evidence. That's what I have discovered anyway. am in my first IVF cycle and found almost everything I found searching and posting online to be conflicting, inacurate, etc. So, I'd suggest taking *everything* you read here any anywhere with a large grain of salt and ask your RE.

[Anonymous]

OP according to my internet RE you can't lower FSH (menopur/gonal f) doses without shrinking existing follicles or lowering Estradiol so it sounds like this cycle may be a bust but you are not a hopeless case especially with that initial response.

[Anonymous]

Thanks all. Your words are very comforting.

I was very frustrated to learn that I will simply have to eat $2000 of the $2500 for this cycle. Retrospectively, I would have rather kept up the high dose and converted to IVF (vs. trying to control things with a lowered dose) knowing now that lowering the dose may have been the bigger risk. Ah well. I also really wanted to make an IUI work (mostly because I am afraid of surgery and because I liked the idea of avoiding injections and lots of progesterone during a first trimester) so maybe I would have pushed for conservative treatment anyway.

[Anonymous]

Look at it this way, since you respond so well to medication, your IVF retrieval should be able to obtain a large number of eggs. And this means you will have a good chance for frozen embryos for future FET cycles. And this means the worst part of IVF, the actual retrieval, may only have to be done once for you. GOod luck!

[Anonymous]

Anonymous wrote:Look at it this way, since you respond so well to medication, your IVF retrieval should be able to obtain a large number of eggs. And this means you will have a good chance for frozen embryos for future FET cycles. And this means the worst part of IVF, the actual retrieval, may only have to be done once for you. GOod luck!

To me retrieval is the easiest part.