Leucovorin/Folinic Acid

[Anonymous]

Anonymous wrote:

Anonymous wrote:Pp, are you seeing good results with leucovorin? What pharmacy has it? How old is your child? Are you also giving B12 or any other supplements with it? Did your pediatrician want additional bloodwork besides the FRAT like a CBC, folate levels?

Yes. He is high functioning so we saw improvement is his conversation skills- more talkative, less trailing off or one word answers. We also saw improvements in social communication like more expressive, better eye contact. Surprisingly we also see less rigidity like trying new foods or switching tasks. All around hes becoming a happier, easy going person.

We arent giving any other supplement. We checked his homocysteine, methylmalonic acid, b12 and did an iron panel while waiting for the frat test results. He's not deficient so there isnt need to supplement.

All pharmacies have it. We get ours from CVS.
Our child is young adult age.

What dosage are you using?

[Anonymous]

Anonymous wrote:We tried the OTC methylfolate with no effect. I'm in an online group and several people have gotten leucovorin. Nobody has reported dramatic improvement, some think it might be a little helpful but hard to say. Wondering if it's worth pursuing.

Its doubtful that youre at the correct dose with over the counter folinic acid. For example we dont see effect at 100 mg but see dramatic effects at 150 mg.

[Anonymous]

DS 13yo now up to 25mg twice daily and seeing more attention, more talkative (was already verbal), and no significant side effects. We are doing a compounded version that is pure folinic acid without fillers.

[Anonymous]

My 6yo son has been on leucovorin for about 4 months now at a 25 mg twice daily dosage. For the past two weeks he has been more irritable and oppositional. Have you had this experience? Not sure if it's related to the treatment or something else.

[Anonymous]

Bump

[Anonymous]

Anyone have suggestions on where to read more about this?