Experimental Drug Eases Autistic Behaviors in Mice

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Experimental Drug Eases Autistic Behaviors in Mice
Whether it would work on humans is still unknown, researchers say
April 25, 2012

By Jenifer Goodwin
HealthDay Reporter
WEDNESDAY, April 25 (HealthDay News) -- An experimental drug reduced two signature characteristics of autism -- repetitive behavior and abnormal social interactions -- in laboratory mice, new research finds.
The drug, GRN-529, targets glutamate, a major neurotransmitter found throughout the brain that's involved with activating neurons, or brain cells. Researchers believe the compound works through a specific glutamate receptor (mGluR5) and decreases glutamate activity.

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