Mosaic Embryos

[Anonymous]

Freeze.

[Anonymous]

Anonymous wrote:OP: You would know if it's mosaic embryo. From your post, it sounds like it is an abnormal embryo but your title suggests that it's a mosaic embryo. I recently have this conversation with my RE, who said that we would know if it's a mosaic embryo from the PGS testing.

Also, someone suggest transferring the abnormal embryo during non fertile period. I am not sure where you are at, OP, but SG would not allow that to happen. I also asked.

OP here. I guess this is why I am confused. My RE gave the report over the phone. She said one was abnormal because of Chromosome 21 and was not compatible with life and would lead to a miscarriage if it even implanted. The other one she said was considered abnormal because it was missing information on Chromosome 11, and that I had a choice to discard it since it was at the momennt no way to i guess tell if it was abnormal or not, therefore it was considered abnormal. She said some people hold onto them in the event later down the line it was a way to get more information on it. Later in an email, my nurse then referred to it as mosaic.

While I have a calll in the the RE for more clarity, because it was a lot to take in initally... I was googling and getting confused. I saw some reports saying that mosaic embroys still have a chance of correcting itself and go on to become healthy babies. I admittedly am unclear on which I have and was hoping to see what folks here had to say.

We are at SG, but we arent interested in transferring in a non fertile period. I just didnt want to make a rash decision on an embryo that may be viable down the line.

THANKS!

[Anonymous]

Anonymous wrote:

Anonymous wrote:OP: You would know if it's mosaic embryo. From your post, it sounds like it is an abnormal embryo but your title suggests that it's a mosaic embryo. I recently have this conversation with my RE, who said that we would know if it's a mosaic embryo from the PGS testing.

Also, someone suggest transferring the abnormal embryo during non fertile period. I am not sure where you are at, OP, but SG would not allow that to happen. I also asked.

OP here. I guess this is why I am confused. My RE gave the report over the phone. She said one was abnormal because of Chromosome 21 and was not compatible with life and would lead to a miscarriage if it even implanted. The other one she said was considered abnormal because it was missing information on Chromosome 11, and that I had a choice to discard it since it was at the momennt no way to i guess tell if it was abnormal or not, therefore it was considered abnormal. She said some people hold onto them in the event later down the line it was a way to get more information on it. Later in an email, my nurse then referred to it as mosaic.

While I have a calll in the the RE for more clarity, because it was a lot to take in initally... I was googling and getting confused. I saw some reports saying that mosaic embroys still have a chance of correcting itself and go on to become healthy babies. I admittedly am unclear on which I have and was hoping to see what folks here had to say.

We are at SG, but we arent interested in transferring in a non fertile period. I just didnt want to make a rash decision on an embryo that may be viable down the line.

THANKS!

I went through SG's required instructional videos about PGS and they explained that embryos that cannot be classified as normal or abnormal are actually inconclusive. I hope you freeze it until PGS technology gets improved and it's able to provide more information. They already have the embryo's DNA sequence so they would not need to biopsy it again but would hopefully be able to provide more information about the missing information on chromosome 11.

[Anonymous]

Anonymous wrote:Did you read the article on genetic repair in yesterday's Post. This is not going to happen in our lifetime in any kind of widely available way, even if it does happen scientifically.

Have you read the article yourself? The repair was done on the sperm. THEN they fertilized the egg, so the resulting embryo had the "edits".

[Anonymous]

Anonymous wrote:For religious reasons, we wouldn't discard, but would do the transfer during a non-fertile time.

How is this different than discarding? I'm not being judgemental but just wondering how, from a religious perspective, letting a clinic discard vs. discarding in your uterous isn't the same?

[Anonymous]

Anonymous wrote:

Anonymous wrote:For religious reasons, we wouldn't discard, but would do the transfer during a non-fertile time.

How is this different than discarding? I'm not being judgemental but just wondering how, from a religious perspective, letting a clinic discard vs. discarding in your uterous isn't the same?

I am genuinely wondering the same. I haven't heard of this before so just want to understand the rationale.