Gestational Carrier with PGS tested embryos - can it still not work?

[Anonymous]

When we were considering this route the lawyer we spoke with said that the GS genetic compatibility is definitely a factor, which actually led her to believe in the immune component of this.

She had seen instances where PGS normal embryos worked with one GS but not another. Some woman (genetically) are very receptive to any other embryo implanting in their uterus. There is so much involved it's impossible to know all the factors but reproductive immunology is getting closer and closer every day.

[Anonymous]

I'd suggest talking to an RE about this vs. getting the lawyer's advice. Went through GC & know many others & never have heard any of the immunology stuff before. It you have a generally healthy surrogate - it usually depends on the egg quality more than anything.

[Anonymous]

Anonymous wrote:I've done 5 IVF cycles (2 with own eggs and 3 with donor eggs). The embryos with donor eggs were all PGS tested and still all 3 failed to implant. We are pretty much out of hope and out of money. We still have 4 more PGS tested embryos frozen and are now considering a gestational carrier. It 's very expensive and would involve taking a home equity loan for us to afford it. We're prepared to do that if this is truly the solution to building our family. But after all the hope and disappointment we've been through, I'm wondering if this is really a sure thing. For anyone out there who had used a carrier, can you reply to let me know if it worked and if so, after how many tries? I would also being interested in hearing from anyone who did not have success going this route. Thank you!

New poster here. After going through 8 IVFs (6 transfers), we tried transferring PGS normal embryos in 2 different surrogates. One of the surrogates was also a proven surrogate. Both GCs ended up with BFN. So yes, it's possible that PGS normal embryos might not work even in GC. There could be multiple reasons: (1) Not all PGS normal embryos are supposed to implant, they just have a better success rates and those 2 transferred were not meant to be, (2) Embryos were created using my eggs and husband's sperm. Although PGS normal, the egg or sperm or both could be of bad quality, (3) Just bad luck.