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My experience is pretty similar to 22:36. My DH had suffered from depression for years and it took a lot of counseling (individual and couples) for him to accept there was a problem and then agree to medication. He used Wellbutin very successfully with few negative side affects - the was one unexpected positive side effect, his desire for cigarettes diminished greatly and he was able to quit smoking. After a few years, he went off, was off for a few years but then needed to go back on medication. Wellbutrin didn't do it for him any more. He ended up on Cymbalta and it's really made a significant difference. It is hell being with someone who's depressed and if he hadn't gotten it under control, we would be divorced by now. The unfortunate side effect is that while erections aren't a problem, he has trouble ejaculating. It's frustrating for him but he says he feels so much better now that his depression is under control that it's worth the trade off.
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