What should we do?

[Anonymous]

Anonymous wrote:IUI doesn't do much more than intercourse does. If you do either with Clomid there's a chance of multiples. At your age and with the benefit about to expire, I would 100% do IVF. See what embryos you get. If you don't get anything good you can reassess your options (donor egg?). And your egg quality is going to decline pretty steeply, so might as well freeze embryos from 42-year-old eggs and not 42.5 or 43-year-old eggs.

Why do iui then if it doesn’t do much more than intercourse?

[Anonymous]

Anonymous wrote:

Anonymous wrote:IUI doesn't do much more than intercourse does. If you do either with Clomid there's a chance of multiples. At your age and with the benefit about to expire, I would 100% do IVF. See what embryos you get. If you don't get anything good you can reassess your options (donor egg?). And your egg quality is going to decline pretty steeply, so might as well freeze embryos from 42-year-old eggs and not 42.5 or 43-year-old eggs.

Why do iui then if it doesn’t do much more than intercourse?

Iui is great if you don't ovulate naturally- I took letrozole, frequent monitoring with a reproductive endocrinologist and then timed it. Dr said timed intercourse ( aka letrozole plus frequent ultrasounds and bloodwork plus sex) would be equivalent... my husband takes a medicine we were anxious impacted sperm so we did iui. No clue why an ob would do letrozole if you already ovulate on your own.

[Anonymous]

Coming from someone age 41 who has been at this game for quite a while... At age 42, statistically speaking, most of your eggs will be abnormal. With IUI, you're trying to get pregnant with 1-3 eggs in any given month. Chances are, those eggs will all be abnormal (euploid rate at age 42 is about 10-20% on average). If they are all abnormal, you either won't have implantation, will have a chemical, or will have a miscarriage. This is why the success rate of an IUI at age 40+ is so very low. IUIs are much more successful in younger populations. If you have a miscarriage several weeks in, you will also deal with a loss in time. With IVF and your AMH, you'll likely get a good number of eggs to fertilize. Ideally, with a good number of eggs, you will then get multiple embryos. From there, you can then decide if you want to PGA test. Success with natural conception at age 42 typically takes quite a while, if it is ever attained. Using IVF is substantially more efficient.