Estradiol reaction

Anonymous
Hi. Has any one had a reaction or side effects from using this cream? Due to vaginal discomfort and cysts forming, my GYN prescribed the cream. I am to insert it every night for 2 weeks and then twice a week thereafter. Last night was my first dose. This morning I woke up with intestinal cramping, dizziness, and a racing heart rate. It did improve as the day went on but I still don’t feel quite right. Could it be the cream? I am afraid to use it again tonight!
Anonymous
How much, just 1 gram? That's weird. Talk to Doctor. Do you have tears or breaks in vaginal lining?
Anonymous
Are you sure you got the right cream?

I'd call the doctor before using it again.

Anonymous
This cream made a big difference to me with discomfort during intercourse- for the better. I had none of the side effects you listed. FYI and TMI?- after a few times I also started applying without the applicator for a more local and cleaner application?
Otherwise I would recommend talking to your doctor.
Anonymous
My mom started it a few months ago, and she also complained about the side effects. Mainly abdominal pain and cramping. The days she was applying it, she looked (and felt) sick.
Anonymous
You may not need the full dose twice a week, and especially not the two-week daily “loading dose” often recommended—many women don’t and are irritated by that amount.

Many apply a pea-size amount topically/externally, and a pea-size amount internally, twice a week.

Also, once the tissue begins to improve, the cream may not absorb as readily (which might also improve side effects).

I think the gastro upset, especially at higher doses, can happen at first, but it probably shouldn’t continue long-term—check with your doctor if it does.

https://www.goodrx.com/estradiol/applying-estrogen-cream
Anonymous
OP here - yes 1 gram. Should I reduce the dose at least initially? Maybe it was just a coincidence?

How would I know if I have tears. The GYN did not say I did. I went in because I got a giant cyst. I had no clue what it was!
Anonymous
Anonymous wrote:OP here - yes 1 gram. Should I reduce the dose at least initially? Maybe it was just a coincidence?

How would I know if I have tears. The GYN did not say I did. I went in because I got a giant cyst. I had no clue what it was!


My dose is just 1/2 gram. Maybe you can try that first.
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