Esophageal eosophinilia and avoiding omeprazole bc of dementia risk?

[Anonymous]

Esophageal eosophinila diagnosed by endoscopy. Practically speaking: thin and ribbed esophagus leads to food getting stuck/choking.

DR prescribed omezaprole, which is primarily for acid reflux…which I don’t have. Recent studies flagged a link to dementia risk, which worries me.

Anyone btdt with either the diagnosis or avoiding omezaprole?

[Anonymous]

My gastroenterologist told me that the dementia risks are overstated.

[Anonymous]

Anonymous wrote:My gastroenterologist told me that the dementia risks are overstated.

Mine too. I’m not sure I believe her though. I’ve tried weaning myself off and I swear this drug is addictive. The rebound effects are terrible.

[Anonymous]

Lot of people take PPIs for decades. I will take some increase in the risk for dementia vs some esophagus cancer and constant stomach discomfort. I do recommend supplementing with b12, K2, vitamin D, Calcium, etc. to avoid some of the long term risks with PPIs. At this point I am sort of resigned to taking them indefinitely.

[Anonymous]

Quick googling shows that the dementia risk is not that clear cut at all. Just stay active and exercise and take b12

[Anonymous]

Anonymous wrote:My gastroenterologist told me that the dementia risks are overstated.

Mine did too.

[Anonymous]

Euthanasia before you get dementia

[Anonymous]

There’s been a well documented uptick in dementia in recent years, and something must be causing it. It could be these meds plus all the people taking melatonin and other sleep aids which have also been linked to dementia.

[Anonymous]

In October 2023, AstraZeneca settled Prilosec lawsuits in New Jersey and Delaware for $425 million.

^^^
Seems like there must be sufficient evidence pointing to a link with dementia for such a settlement.

[Anonymous]

You don’t have a real choice here. A well-characterized drug may fully control a health problem that will otherwise seriously curtail your life, if it does not actually limit it. There is a distant and not fully proven risk of a bad effect that may occur anyway. Take the PPI.

[Anonymous]

Have you rid your house of dust mites? Do you have a pet?

Have you tried a food elimination diet? https://www.nih.gov/news-events/news-releases/forgoing-one-food-treats-eosinophilic-esophagitis-well-excluding-six#:~:text=Excluding%20certain%20foods%20from%20the,signs%20and%20symptoms%20of%20EoE.
If you go gluten and dairy free you need to give it at least a 10-12 week trial.

Mom just died from dementia in April. She was on a high dose omeprazole for decades.
Six years ago, I was able to get her off of the omeprazole but it took 8 months of a long slow taper and I moved her to a simple diet.

I would personally modify my diet before gong on PPI's after having a loved one die of dementia (who was on PPI's for decades.)

[Anonymous]

Anonymous wrote:

Anonymous wrote:My gastroenterologist told me that the dementia risks are overstated.

Mine too. I’m not sure I believe her though. I’ve tried weaning myself off and I swear this drug is addictive. The rebound effects are terrible.

Gastroenterologists don't have much to offer for acid reflux treatment other than PPI's and Americans don't want to stop eating pizza and drinking wine.

I got Mom off of PPI's but it took simplifying her diet and a long slow 8 month taper to get her off of the PPI's.

[Anonymous]

Anonymous wrote:Have you rid your house of dust mites? Do you have a pet?

Have you tried a food elimination diet? https://www.nih.gov/news-events/news-releases/forgoing-one-food-treats-eosinophilic-esophagitis-well-excluding-six#:~:text=Excluding%20certain%20foods%20from%20the,signs%20and%20symptoms%20of%20EoE.
If you go gluten and dairy free you need to give it at least a 10-12 week trial.

Mom just died from dementia in April. She was on a high dose omeprazole for decades.
Six years ago, I was able to get her off of the omeprazole but it took 8 months of a long slow taper and I moved her to a simple diet.

I would personally modify my diet before gong on PPI's after having a loved one die of dementia (who was on PPI's for decades.)

No, just no

[Anonymous]

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:My gastroenterologist told me that the dementia risks are overstated.

Mine too. I’m not sure I believe her though. I’ve tried weaning myself off and I swear this drug is addictive. The rebound effects are terrible.

Gastroenterologists don't have much to offer for acid reflux treatment other than PPI's and Americans don't want to stop eating pizza and drinking wine.

I got Mom off of PPI's but it took simplifying her diet and a long slow 8 month taper to get her off of the PPI's.

Grow up. I don’t drink and rarely eat pizza.

[Anonymous]

Anonymous wrote:There’s been a well documented uptick in dementia in recent years, and something must be causing it. It could be these meds plus all the people taking melatonin and other sleep aids which have also been linked to dementia.

We’ve never had this many people living to be this old with studies done on them, so do we really know if it’s more common?

Also, diet and exercise probably has a lot to do with it.