Zepbound fatigue

[Anonymous]

I am only 4 weeks in and still on the starter dose of compounded Zepbound.
Minor nausea, occasional headaches though that seems to have subsided. These side effects are really very minor. Ginger pills help nausea. Mostly I feel disinterested in food - especially bread and cookies!

What I’m struggling with is fatigue. The timing seems consistent with the start of Zepbound. I’m just exhausted. I’m yawning and finding it hard to stay awake early in the day. By mid afternoon, I feel tired but not nearly as much as in the morning.

I’ve heard this can get better in time. Anyone have personal experience to share?

[Anonymous]

I’m in Mounjaro (same med) and had lots of fatigue when starting out. It started to lessen as I went up to 7.5 and 10.

I’m now on 15 and still get bouts of it. Usually on shot day I have a burst of energy and the day after I may need a midday nap. It’s much better than when I started - I didn’t want to get out bed!

[Anonymous]

I wonder if you need more protein. If you aren't interested in food, are you still eating enough?

[Anonymous]

It’s normal. I’m on Ozempic, and when I started, it felt like the first trimester all over again. It gets better over time. It would return when I stepped up the dose.

Hang in there.