Thyroid cancer and weight loss medication

[Anonymous]

I went to a nurse practitioner yesterday since my doctor was so booked up for my yearly physical. I inquired into weight loss medication since I am obese. The nurse practitioner told me that she could not prescribe any medication for weight loss if I had a family history of thyroid or pancreatic cancer (I do not) and some other things about the medication.

After hearing that I am nervous about trying it and am now considering other alternatives. Is there really a link between these two things?

[Anonymous]

Apparently there may be a link. So I’m going to sit this boom out and be a little chubby until they know for sure.

[Anonymous]

Anonymous wrote:Apparently there may be a link. So I’m going to sit this boom out and be a little chubby until they know for sure.

+100 SAME. Better to be a little overweight and healthy than skinner and sick. No thanks!

[Anonymous]

I feel like whenever you mess around with the thyroid -HRT, weight loss meds, anything with metabolism and hormones - there's a risk of introducing "something ".

[Anonymous]

I haven’t heard about pancreatic cancer risk. Thyroid yes, but it’s a specific type. For many people the cardiac benefits are stronger than the cancer risk.

[Anonymous]

I read about this-the risk of thyroid cancer was really really really low. Way lower than my risk of heart disease, heart attack, or stroke. Not to mention stuff like high cholesterol that being overweight can cause.

[Anonymous]

Also, Semaglutide has been used for nearly 2 decades at this point so it appears to be safe. I don't know about the other meds (semaglutide is used in Ozempic/Wegovy, not sure about others)

[Anonymous]

It’s a specific kind of thyroid cancer that runs in families. Per my doctor, if no one in your extended family has had this cancer you don’t need to worry about it.

[Anonymous]

I believe that the current theory is that it reduces pancreatic cancer risk, which is highly correlated to obesity.

[Anonymous]

Semaglutides do have a risk for pancreatitis (why I won't take them--had it once and it was brutal, not to mention dangerous). Chronic pancreatitis is linked to pancreatic cancer, but I don't think acute is.

[Anonymous]

Anonymous wrote:Semaglutides do have a risk for pancreatitis (why I won't take them--had it once and it was brutal, not to mention dangerous). Chronic pancreatitis is linked to pancreatic cancer, but I don't think acute is.

I think you are right: It is just chronic. I would probably not take them if I had a history of acute pancreatitis.

I do not believe there is any evidence that in the twenty or so years semaglutides have been used for diabetics that there has been an increase in pancreatic cancer. If anything there has been a decrease.

[Anonymous]

The people in the mounjaro trial had to sign a waiver that they were aware of the risk for pancreatic cancer. I mentioned this here before and everyone told me I was insane but I know it’s true.

[Anonymous]

Anonymous wrote:The people in the mounjaro trial had to sign a waiver that they were aware of the risk for pancreatic cancer. I mentioned this here before and everyone told me I was insane but I know it’s true.

This is so not true. I was in the original trial for Mournjaro for weight loss and we signed no such waiver. Now in a trial for maintenance and again,I signed no such waiver. There are real concerns regarding pancreatitis. Several people in our trial had pancreatitis.

[Anonymous]

Anonymous wrote:

Anonymous wrote:The people in the mounjaro trial had to sign a waiver that they were aware of the risk for pancreatic cancer. I mentioned this here before and everyone told me I was insane but I know it’s true.

This is so not true. I was in the original trial for Mournjaro for weight loss and we signed no such waiver. Now in a trial for maintenance and again,I signed no such waiver. There are real concerns regarding pancreatitis. Several people in our trial had pancreatitis.

Thank you for clarifying!

[Anonymous]

My oncologist was very in favor of my taking mounjaro.my starting point was 40 lbs overweight, but not obese. Being overweight is a risk factor for recurrence of cancer.