Clomid Depression

[Anonymous]

Anyone experience severe depression with Clomid?

[Anonymous]

I don't know about severe, but clomid caused depression symptoms for me.

I don't suffer from depression, and when I was on clomid I felt horrible. Really sad, hopeless, not caring about anything, would sometimes just start crying for no real reason while I was in the car alone -- things that are not like me and that I knew didn't feel "normal." And I don't think it was depression/sadness from fertility issues (though perhaps it can be hard to distinguish, depending on the circumstances?) because I honestly wasn't all that stressed about the fertility aspect at that point, I had just started working with an RE and I was very hopeful & optimistic. And I felt better as soon as I got off the clomid.

[Anonymous]

Yep -- you just described how I have been feeling exactly. And even though I know it's not normal for me and probably not based in reality, it still is very difficult to get through. Thanks. -- OP

[Anonymous]

I felt that way, and it got worse with each Clomid cycle we did (I did 5 total.)

[Anonymous]

I had severe depression with clomid and I only did one cycle, luckily I did not experience the same symptoms with the injectables for IVF and I got pregnant with the first cycle. I had a similar experience with bcp's so it seems that only synthetic hormones cause difficulty, but natural stuff was okay.

[Anonymous]

Yes, horrible depression on clomid. Couldn't stand it and luckily only did one cycle on. Also doing injectables and have not experienced the same problems.

[Anonymous]

I wouldn't say severe depression, but it does make me really weepy about stuff that wouldn't normally cause that type of reaction (like, even remotely).