Anonymous
11/13/2025 02:45
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:This is still a very dangerous move- it still needs a warning. There are women who now believe that HRT has no connection whatsoever with cancer, that bioidentical hormones are actually a new thing- that they are better than "older synthetic" hormones and that everything is just perfectly safe, but actually it's just a marketing term. And that just isn't true! Hormones are still a risk/ benefit medication and there's a lot of nuance regarding this.
Women are working longer, living longer, and want to remain relevant longer. That's all good. But menopause happens earlier than everyone expects and we all know it ages us.Everyone has piled on this as if older women were lied to. They weren't. They are still hormones.
HRT is huge industry. It's not a panacea.
Are you a medical researcher? Are you a male?
Obviously no doctor prescribes HRT without going over the risks. Mine ran multiple tests as well, so we had all the data points.
But you know what, for the first time in my life, my cholesterol and triglycerides were high---cholestrol went from 150/160 for the last 10+ years and during first 1.5 years of menopause went up consistently to over 238. No diet changes (except for the better---even cleaner eating than before and more fruits and veggies). 6 months after HRT, it's going back down. Triglycerides had been around 60-70, went up to 140 and are also back down.
So I'll weigh the cardiovascular benefits with the other risks and make my choice.
Also, have family history of osteoporosis, so far I am still good, but doctor says this choice will help prevent it (certainly much more than not taking HRT).
So yes it's not a panacea, but most doctors and researchers now believe the health benefits for most people outweigh the small risks. I'm already seeing the health benefits and will be thrilled to see it continue.
Sorry, this will not prevent osteoporosis. And no, most doctors do not now believe the risks outweigh the benefits. At all.
Anonymous
11/13/2025 02:43
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I don’t trust anything RFK jr or trump says. This FDA is currently SUS so I’m seeing this as a red flag. If they promote it, I should not consider it.
If it was legitimately safe, Melania should have made the announcement. Woman to women.
I’ll wait until we have actual medical experts back in the FDA before I trust their advice.
Wow - you would have given it more credence out of Melania’s mouth? That’s moronic.
HRT has enabled me to sleep through the night regularly for the first time in a year. Game changer.
And has increased your risk of stroke and cancer.
Well, my thyroid stopped working in my 20s and I need thyroid replacement hormone for the rest of my life to function because my body doesn’t make thyroid hormone anymore. Does that raise my risk of stroke and cancer? I don’t know, maybe. But I’d rather die than live half dead. I don’t see how it’s different with progesterone and estrogen.
You don’t see how thyroid hormones and estrogen/progesterone are different? Ok.
Why are estrogen/progesterone sacrosanct? One hormone is okay but not the other?
I had intense throwing up level menstrual cramps as a teen. BC was the miracle solution. Yet, those cramps were natural. Should I have just suffered?
What? Yes, one hormone is not at all like the other. Full stop.
You are very very confused.
Anonymous
11/12/2025 21:32
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I just talked about this yesterday with my ob/gyn. That label and study that caused it created unnecessary misery for many women.
This is the right move.
I'm mid-40s and feel terrible that my mom went through menopause in the early 2000s after the study that scared everyone away from MHT. A lot of unnecessary suffering.
Have you ever thought that 25 years later the formulation is gonna be very different and now it’s safer?
+1
The old version was made out of pregnant horse urine. The new one isn’t and is bioidentical. That’s not to say there are no risks but it’s much safer.
They also have bioidentical progesterone.
“Bio identical” isn’t a thing.
She may have meant “bio equivalent “.
Which also isn't a thing.
Bio equivalent is a thing - generic drugs are bio equivalent to branded drugs. It’s just the wrong thing for this context.
Anonymous
11/12/2025 21:25
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I don’t trust anything RFK jr or trump says. This FDA is currently SUS so I’m seeing this as a red flag. If they promote it, I should not consider it.
If it was legitimately safe, Melania should have made the announcement. Woman to women.
I’ll wait until we have actual medical experts back in the FDA before I trust their advice.
Wow - you would have given it more credence out of Melania’s mouth? That’s moronic.
HRT has enabled me to sleep through the night regularly for the first time in a year. Game changer.
And has increased your risk of stroke and cancer.
Well, my thyroid stopped working in my 20s and I need thyroid replacement hormone for the rest of my life to function because my body doesn’t make thyroid hormone anymore. Does that raise my risk of stroke and cancer? I don’t know, maybe. But I’d rather die than live half dead. I don’t see how it’s different with progesterone and estrogen.
You don’t see how thyroid hormones and estrogen/progesterone are different? Ok.
Why are estrogen/progesterone sacrosanct? One hormone is okay but not the other?
I had intense throwing up level menstrual cramps as a teen. BC was the miracle solution. Yet, those cramps were natural. Should I have just suffered?
Ffs. Nobody said any hormone is “sacrosanct.” The point is that your thyroid failing in your 20s is totally different from menopause in your 50s. To compare the two is nonsensical.
I don’t think anyone is suggesting that people go on HRT for the rest of their lives. Often it’s for a specific time span until your symptoms subside. If you don’t have bothersome symptoms, don’t take it.
Actually I do think people are talking about that now, particularly for bone density.
Anonymous
11/12/2025 20:50
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I don’t trust anything RFK jr or trump says. This FDA is currently SUS so I’m seeing this as a red flag. If they promote it, I should not consider it.
If it was legitimately safe, Melania should have made the announcement. Woman to women.
I’ll wait until we have actual medical experts back in the FDA before I trust their advice.
Wow - you would have given it more credence out of Melania’s mouth? That’s moronic.
HRT has enabled me to sleep through the night regularly for the first time in a year. Game changer.
And has increased your risk of stroke and cancer.
Well, my thyroid stopped working in my 20s and I need thyroid replacement hormone for the rest of my life to function because my body doesn’t make thyroid hormone anymore. Does that raise my risk of stroke and cancer? I don’t know, maybe. But I’d rather die than live half dead. I don’t see how it’s different with progesterone and estrogen.
You don’t see how thyroid hormones and estrogen/progesterone are different? Ok.
Why are estrogen/progesterone sacrosanct? One hormone is okay but not the other?
I had intense throwing up level menstrual cramps as a teen. BC was the miracle solution. Yet, those cramps were natural. Should I have just suffered?
Ffs. Nobody said any hormone is “sacrosanct.” The point is that your thyroid failing in your 20s is totally different from menopause in your 50s. To compare the two is nonsensical.
Is it more nonsensical than posting cherry-picked facts about potential risks while deliberately ignoring the data that suggest HRT lowers all-cause mortality?
All medical societies say that there are risks.
And the research shows use of Estrogen patch along with oral progesterone lowers a woman's overall mortality. So in the end, you have more risks of dying if you don't take it (when you need it) than taking it.
In most cases, the benefits far outweigh the "risks"
No “the research” does not show that.
Anonymous
11/12/2025 20:47
Subject: FDA removed black box warning for HRT
Anonymous wrote:This is still a very dangerous move- it still needs a warning. There are women who now believe that HRT has no connection whatsoever with cancer, that bioidentical hormones are actually a new thing- that they are better than "older synthetic" hormones and that everything is just perfectly safe, but actually it's just a marketing term. And that just isn't true! Hormones are still a risk/ benefit medication and there's a lot of nuance regarding this.
Women are working longer, living longer, and want to remain relevant longer. That's all good. But menopause happens earlier than everyone expects and we all know it ages us.Everyone has piled on this as if older women were lied to. They weren't. They are still hormones.
HRT is huge industry. It's not a panacea.
Are you a medical researcher? Are you a male?
Obviously no doctor prescribes HRT without going over the risks. Mine ran multiple tests as well, so we had all the data points.
But you know what, for the first time in my life, my cholesterol and triglycerides were high---cholestrol went from 150/160 for the last 10+ years and during first 1.5 years of menopause went up consistently to over 238. No diet changes (except for the better---even cleaner eating than before and more fruits and veggies). 6 months after HRT, it's going back down. Triglycerides had been around 60-70, went up to 140 and are also back down.
So I'll weigh the cardiovascular benefits with the other risks and make my choice.
Also, have family history of osteoporosis, so far I am still good, but doctor says this choice will help prevent it (certainly much more than not taking HRT).
So yes it's not a panacea, but most doctors and researchers now believe the health benefits for most people outweigh the small risks. I'm already seeing the health benefits and will be thrilled to see it continue.
Anonymous
11/12/2025 20:43
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I just talked about this yesterday with my ob/gyn. That label and study that caused it created unnecessary misery for many women.
This is the right move.
I'm mid-40s and feel terrible that my mom went through menopause in the early 2000s after the study that scared everyone away from MHT. A lot of unnecessary suffering.
Have you ever thought that 25 years later the formulation is gonna be very different and now it’s safer?
+1
The old version was made out of pregnant horse urine. The new one isn’t and is bioidentical. That’s not to say there are no risks but it’s much safer.
They also have bioidentical progesterone.
“Bio identical” isn’t a thing.
She may have meant “bio equivalent “.
Which also isn't a thing.
Anonymous
11/12/2025 20:42
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I just talked about this yesterday with my ob/gyn. That label and study that caused it created unnecessary misery for many women.
This is the right move.
I'm mid-40s and feel terrible that my mom went through menopause in the early 2000s after the study that scared everyone away from MHT. A lot of unnecessary suffering.
Have you ever thought that 25 years later the formulation is gonna be very different and now it’s safer?
+1
The old version was made out of pregnant horse urine. The new one isn’t and is bioidentical. That’s not to say there are no risks but it’s much safer.
They also have bioidentical progesterone.
Bioidentical is nothing different. Please stop this nonsense.
Anonymous
11/12/2025 20:42
Subject: FDA removed black box warning for HRT
Anonymous wrote:I think it’s still not good for some women right? I have family history of ovarian and uterine and colon and have been told it would be unsafe for me.
And it is. You certainly wouldn't take HRT with a family history of cancer. No one said there wasn't a causation of HRT and cancer. There absolutely is. It's just now it’s being rebranded.
Anonymous
11/12/2025 20:40
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:I just don’t know why most women would need to “treat” a normal biological process.
(I say this as a post menopausal woman)
Same reason I didn't just let blood run down my leg before menopause. (I say this as a woman using HRT!)
What? This makes no sense, but I'm sure you know that.
Anonymous
11/12/2025 20:39
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I don’t trust anything RFK jr or trump says. This FDA is currently SUS so I’m seeing this as a red flag. If they promote it, I should not consider it.
If it was legitimately safe, Melania should have made the announcement. Woman to women.
I’ll wait until we have actual medical experts back in the FDA before I trust their advice.
Wow - you would have given it more credence out of Melania’s mouth? That’s moronic.
HRT has enabled me to sleep through the night regularly for the first time in a year. Game changer.
And has increased your risk of stroke and cancer.
Well, my thyroid stopped working in my 20s and I need thyroid replacement hormone for the rest of my life to function because my body doesn’t make thyroid hormone anymore. Does that raise my risk of stroke and cancer? I don’t know, maybe. But I’d rather die than live half dead. I don’t see how it’s different with progesterone and estrogen.
You don’t see how thyroid hormones and estrogen/progesterone are different? Ok.
They are both hormones our bodies need (as females). Women are 3-4 times "healthier" and at less risk for serious issues that typically kill men (think heart attack/stroke/etc), until we go thru menopause. Then our rates skyrocket and we become "very unhealthy" because the lack of hormones. Get on the proper hormones and you can be happier and healthier in many ways.
I don't want to live from early 50s until 85/90 without those hormones. With them, I'll take the risks that might come (of which apparently they are minimal). Most of you take way more risks with drinking and eating crap and not exercising, yet don't care to change that
Are you under the impression you will take HRT until you are 95?
Not at all. But if the 10 years I can take it helps me live to 95 and be happy and less likely to fall and break a hip, I'm all for it. If it also means I can have sex without feeling like someone is rubbing sandpaper in my vagina, despite the entire tube of lube I have used, then yes it means I will weigh the choices. And being happy is a huge part of being healthy as well.
Anonymous
11/12/2025 20:39
Subject: FDA removed black box warning for HRT
Anonymous wrote:Mark Makary has written several popular books about Medical "truths" that have been discredited. I did some scraping around the internet and his concerns seem valid. I'm glad he's moving forward to make HRT available to American women if needed.
Not all of the Trump administration is a disaster. Makary is a very small bright spot. It doesn't outweigh the other crazies in power, but take the win where you can. Biden's FDA Commissioner was an industry sycophant. Makary has some big picture ideas backed by science.
No, he hasn't. He is thought of in the same sphere as Oz and Kennedy.
Anonymous
11/12/2025 20:37
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I just talked about this yesterday with my ob/gyn. That label and study that caused it created unnecessary misery for many women.
This is the right move.
I'm mid-40s and feel terrible that my mom went through menopause in the early 2000s after the study that scared everyone away from MHT. A lot of unnecessary suffering.
Have you ever thought that 25 years later the formulation is gonna be very different and now it’s safer?
+1
The old version was made out of pregnant horse urine. The new one isn’t and is bioidentical. That’s not to say there are no risks but it’s much safer.
They also have bioidentical progesterone.
“Bio identical” isn’t a thing.
+1. The idea that “bioidentical” hormones are safer is promoted by internet quacks. Even your own exact estrogen made by your own body can be cancer promoting (this is why breast cancer rates go up after pregnancy, when estrogen levels are very high, and after perimenopause, when level spike on and off).
This. It keeps coming up as if it's a new and improved hormone with no risk and all it happens to be is a hormone with a quack name. There is no HRT that matched exactly what is missing. Why is this still going around?
Anonymous
11/12/2025 20:37
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I don’t trust anything RFK jr or trump says. This FDA is currently SUS so I’m seeing this as a red flag. If they promote it, I should not consider it.
If it was legitimately safe, Melania should have made the announcement. Woman to women.
I’ll wait until we have actual medical experts back in the FDA before I trust their advice.
Wow - you would have given it more credence out of Melania’s mouth? That’s moronic.
HRT has enabled me to sleep through the night regularly for the first time in a year. Game changer.
And has increased your risk of stroke and cancer.
Well, my thyroid stopped working in my 20s and I need thyroid replacement hormone for the rest of my life to function because my body doesn’t make thyroid hormone anymore. Does that raise my risk of stroke and cancer? I don’t know, maybe. But I’d rather die than live half dead. I don’t see how it’s different with progesterone and estrogen.
You don’t see how thyroid hormones and estrogen/progesterone are different? Ok.
Why are estrogen/progesterone sacrosanct? One hormone is okay but not the other?
I had intense throwing up level menstrual cramps as a teen. BC was the miracle solution. Yet, those cramps were natural. Should I have just suffered?
Ffs. Nobody said any hormone is “sacrosanct.” The point is that your thyroid failing in your 20s is totally different from menopause in your 50s. To compare the two is nonsensical.
Is it more nonsensical than posting cherry-picked facts about potential risks while deliberately ignoring the data that suggest HRT lowers all-cause mortality?
All medical societies say that there are risks.
And the research shows use of Estrogen patch along with oral progesterone lowers a woman's overall mortality. So in the end, you have more risks of dying if you don't take it (when you need it) than taking it.
In most cases, the benefits far outweigh the "risks"
Anonymous
11/12/2025 20:35
Subject: FDA removed black box warning for HRT
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:I don’t trust anything RFK jr or trump says. This FDA is currently SUS so I’m seeing this as a red flag. If they promote it, I should not consider it.
If it was legitimately safe, Melania should have made the announcement. Woman to women.
I’ll wait until we have actual medical experts back in the FDA before I trust their advice.
Wow - you would have given it more credence out of Melania’s mouth? That’s moronic.
HRT has enabled me to sleep through the night regularly for the first time in a year. Game changer.
And has increased your risk of stroke and cancer.
Well, my thyroid stopped working in my 20s and I need thyroid replacement hormone for the rest of my life to function because my body doesn’t make thyroid hormone anymore. Does that raise my risk of stroke and cancer? I don’t know, maybe. But I’d rather die than live half dead. I don’t see how it’s different with progesterone and estrogen.
No dear, thyroid hormone replacement is not the same as HRT for menopause. It's not the same hormone. If you are not producing thyroid hormone, or you don't have a thyroid- and decide not to take thyroid replacement, you will die. The thyroid manages a lot of systems in your body and it is essential to have.
If you decide not to take menopausal HRT, you will not die. All women lose estrogen, all, not some. It is not a pathology. Underactive or non working thyroid is a pathology. Hormones are not all the same.