I don't drink. Never have. My body cannot process the alcohol so when I drink I go from perfectly sober to I want to die (think the worse hangover you have ever had in your life) without having the pleasant buzz in between. I would rather drink rat poison than alcohol since it has the same effect on me.
That said, my friends, former boyfriends, my DH have never held my lack of drinking against me. I was a VERY social person when I was younger, went to all the parties, openings, fundraisers, signings, etc in NYC literally every night. No one ever held the fact that I never drank alcohol against me. Not a big deal. It just left more booze for everyone else
