Anonymous wrote:I’m on zepbound and have obstructive sleep apnea. Relieved that it’s now an on label use so should keep being approved.

Probably not as a first line treatment. Maybe if you fail a mouthguard and CPAP and BiPap. Insurances companies and and do require you to use and fail less expensive options first.

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Anonymous wrote:Not going away. Trump's new head of FDA and lawsuit will keep compounding in business for the foreseeable future . I would assume insurance and drug manufacturers will figure out how to make the named drugs more accessible and cheaper with the pressure. If not the compounders will keep stealing their business.

Please tell me you are joking. Of course he won’t.

Not joking. Do you know who the nominee is?

Anti COVID vaxx JHU dude.

He is a transplant surgeon and exec at Sesame. All in on compounds. Now with Elon on injections-- here to stay.

You can't be "all in on compounds." There is such a thing as patent law in the US. Full stop.

Do you have any idea how much power Pharma has in the US, anyway?

The compound folks have power too though. I listened to the Barry and Honey Sherman podcast (I know it's Canada) and so much of it was about patent litigation. It's not a given that compounds will lose.

Yes. It is. This isn’t Canada.

Anonymous wrote:Do the posters who say they would never buy drugs from China not realize that the majority of our drugs are manufactured in China and India now and that those factories are not held to the same standards.

Those of you using compounded weight loss drugs really have no idea what is in that mix. The pharmacies are having to scramble just like people using the drugs to find the mixes to make the drugs.

This is crazy.

I mean, which is it? It's terrible that regular drugs are coming from China or that people are buying compounds made in the US because raw ingredients come from China? It makes sense if you shun all meds.

Do the posters who say they would never buy drugs from China not realize that the majority of our drugs are manufactured in China and India now and that those factories are not held to the same standards.

Those of you using compounded weight loss drugs really have no idea what is in that mix. The pharmacies are having to scramble just like people using the drugs to find the mixes to make the drugs.

This is crazy.

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Anonymous wrote:My companies medical coverage BCBS increased by 30% these drugs where the reasons cited for the massive increase. For those of us that don't use these drug this is really messed up.

Thanks to all of you who abused the system to get these when they were not medically necessary. I sat there and never said anything reading all your posts, the constant posts on here about lying about your weight to get these medication, but now I'm mad I have to pay more for those of you lying to get them.

The people lying are lying to get compound with no insurance. It's not affecting your premiums at all.

This and for those who got the name brand, they had to get prior authorization to get them filled…obese and/or severely overweight with comorbidity. So you’re blaming the wrong people.

If compounds go away, I’ll just buy name brand overseas. My doctor already said he would give me physical RXs and then it would be on me to get them filled in Canada or elsewhere. I’ll gladly pay what Canadians are paying.

Anonymous wrote:My companies medical coverage BCBS increased by 30% these drugs where the reasons cited for the massive increase. For those of us that don't use these drug this is really messed up.

Thanks to all of you who abused the system to get these when they were not medically necessary. I sat there and never said anything reading all your posts, the constant posts on here about lying about your weight to get these medication, but now I'm mad I have to pay more for those of you lying to get them.

The people lying are lying to get compound with no insurance. It's not affecting your premiums at all.

Anonymous wrote:I asked my provider again about it this morning, and they again said not to worry about it. Compounds are not going away.

Yeah. This is a really ignorant statement. Which side do you think Republicans are on? Affordable healthcare or letting the free market set the price of drugs.

And I’m not sure where you get the idea Trump can issue an EO and invalidate patent law in the CFRs. He cannot.

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Anonymous wrote:Not going away. Trump's new head of FDA and lawsuit will keep compounding in business for the foreseeable future . I would assume insurance and drug manufacturers will figure out how to make the named drugs more accessible and cheaper with the pressure. If not the compounders will keep stealing their business.

Please tell me you are joking. Of course he won’t.

Not joking. Do you know who the nominee is?

Anti COVID vaxx JHU dude.

He is a transplant surgeon and exec at Sesame. All in on compounds. Now with Elon on injections-- here to stay.

You can't be "all in on compounds." There is such a thing as patent law in the US. Full stop.

Do you have any idea how much power Pharma has in the US, anyway?

Big pharma is really worried right now. FDA makes the designation which allows compounders to thrive. It is fun to watch Lily try to compete with them now.

It starts at the FDA, when they put a drug on the shortage list. But it doesn’t end there. Patent protections are in the statutes, which does allow compounding during shortages. But, if they are on the list and not actually in shortage, then drug companies file in federal Court. And if it gets to SCOTUS, they are ideologically conservative, which makes them more likely to uphold patent law and let the free market do its thing. Trumps justices would vote against carving out an exception to patent law for GLP-1s, because there is nothing in the plain language of the statute that allows it absent an actual shortage.

Anonymous wrote:Elon just posted a pic of himself on X and attributed his slim physique to Mounjaro. He’s said things recently about how Americans should have better access to weight loss drugs. We’ll see.

Interesting to see how that happens when an enormous number of Americans are covered under the VA, Medicare, and Medicaid, which don’t currently cover weight loss drugs. And FEHB, which is required to cover at least one GLP-1, but under increasingly less generous terms that Feds can’t afford. And the government also subsidizes many ACA plans, and would bear at least some of the cost of increased premiums to add these drugs. I’m sure how you square cutting $2T from the federal budget while simultaneously adding such an enormously expensive benefit.

Have you seen the number? It would cost approx $411B dollars to prescribe GLP-1s to the approx 50% of Americans who could benefit (diabetic, obese, overweight with co-morbidities, now includes sleep apnea and early disease, soon to a NASH and addiction). https://cboh.kenaninstitute.unc.edu/publication/glp-1-pricing-conundrums-continue/

In 2022, the entire federal civilian payroll was $271B (the most recent number from a reliable source I could find quickly). And in most agencies, numbers of employees has remained flat since then. I’m SSA which is one of the largest agencies and we have fewer employees per claimant than at any point in the last 40 years. Meanwhile, our cases keep getting more complex. The backlogs are crazy and people are being detailed all over the place to put out the biggest fires in a robbing Peter to pay Paul scheme. There is no fat to trim. And we are not the only agency stretched to the breaking point.

https://www.cbo.gov/publication/60235#:~:text=In%20fiscal%20year%202022%2C%20the,the%20Department%20of%20Homeland%20Security.

https://www.ssa.gov/finance/2024/The%20Social%20Security%20Administration%E2%80%99s%20Major%20Management%20and%20Performance%20Challenges%20During%20Fiscal%20Year%202024.pdf

My point is that if DOGE fired every single federal civilian employees, including those processing SSA claims and make sure checks go out, VA staff, TSA, air traffic control, customs and border control, the IC, civilian DOD, etc— the saving would not pay for GLP-1s for everyone who needs them.

You can’t get the budget down and add over $400B to entitlements. There literally aren’t enough civilian feds for Mump and DOGE to fire to offset the cost.

And NO, Trump cannot EO his way out of Patent law. Actual laws in the CFR protect these patents. A EO cannot over ride a statute. Congress, acting together, could pass a law capping prices, like they did for insulin. But free market capitalist Rs were strongly against that part of the IRA. And the FDA/ MUMP cannot just wave wand and make exceptions to a lawfully issued patent. Novo Nordisk goes to Court, and the patent is enforced.

Now, many of us think it’s ridiculous that Americans pay multiples of what other countries do for meds under patent. But, most of us are Dems, and they have no power for the next 2 years. And even small steps by Dems to bring down some patented drug proaces— letting Medicare negotiate for lower prices on a short list of drugs and capping insulin prices have been met with strong opposition by Rs who want say the free market should determine prices. Well, in the US, the free market believes these drugs are work about $15k a year, per person.

So, which is it Rs? Should drugs be subject to free market capitalism? Or do you want price controls for this one drug because you want to be skinny— which drugs that would cure cancer or slow Alzheimer’s remain out of reach for many Americans? Or do you want to push the deficit up 1/2 a Trillion dollars a year to cover them, while simultaneously promising to lower the deficit by $2T? And if you do add the 400+B to entitlements, where are you cutting to offset this— let alone cutting $2T? You can’t have it all.

Anonymous wrote:My companies medical coverage BCBS increased by 30% these drugs where the reasons cited for the massive increase. For those of us that don't use these drug this is really messed up.

Thanks to all of you who abused the system to get these when they were not medically necessary. I sat there and never said anything reading all your posts, the constant posts on here about lying about your weight to get these medication, but now I'm mad I have to pay more for those of you lying to get them.

Not sure what you are talking about. Compounded drugs are not covered by insurance. People pay out of pocket for them. You should we thanking compounders.

My companies medical coverage BCBS increased by 30% these drugs where the reasons cited for the massive increase. For those of us that don't use these drug this is really messed up.

Thanks to all of you who abused the system to get these when they were not medically necessary. I sat there and never said anything reading all your posts, the constant posts on here about lying about your weight to get these medication, but now I'm mad I have to pay more for those of you lying to get them.

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Anonymous wrote:Not going away. Trump's new head of FDA and lawsuit will keep compounding in business for the foreseeable future . I would assume insurance and drug manufacturers will figure out how to make the named drugs more accessible and cheaper with the pressure. If not the compounders will keep stealing their business.

Please tell me you are joking. Of course he won’t.

Not joking. Do you know who the nominee is?

Anti COVID vaxx JHU dude.

He is a transplant surgeon and exec at Sesame. All in on compounds. Now with Elon on injections-- here to stay.

You can't be "all in on compounds." There is such a thing as patent law in the US. Full stop.

Do you have any idea how much power Pharma has in the US, anyway?

Big pharma is really worried right now. FDA makes the designation which allows compounders to thrive. It is fun to watch Lily try to compete with them now.

I asked my provider again about it this morning, and they again said not to worry about it. Compounds are not going away.

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Anonymous wrote:Not going away. Trump's new head of FDA and lawsuit will keep compounding in business for the foreseeable future . I would assume insurance and drug manufacturers will figure out how to make the named drugs more accessible and cheaper with the pressure. If not the compounders will keep stealing their business.

Please tell me you are joking. Of course he won’t.

Not joking. Do you know who the nominee is?

Anti COVID vaxx JHU dude.

He is a transplant surgeon and exec at Sesame. All in on compounds. Now with Elon on injections-- here to stay.

You can't be "all in on compounds." There is such a thing as patent law in the US. Full stop.

Do you have any idea how much power Pharma has in the US, anyway?

The compound folks have power too though. I listened to the Barry and Honey Sherman podcast (I know it's Canada) and so much of it was about patent litigation. It's not a given that compounds will lose.