My third IUI (+letrozole) just worked! My first is also an IUI baby (clomid) and it worked the second round. Zero issues on my husband's end; I have PCOS.

IUIs are very easy/non-invasive, and SO cheap. Unless you're 38 or something, I think it would be foolish not to try IUI first

It worked for me along with Clomid. I got pregnant (with my now 12 year old) on my second time doing IUI/Clomid.
Neither DH nor I had any issues that showed up in the medical tests we did.

Got pregnant on my third unmedicated/monitored IUI using donor sperm at age 37

I got pregnant on my fourth IUI! I'm so glad we decided to try it before going right to IVF.

I did 6, all failed. Should have stopped at 3.

On the other hand, my friend just got pregnant on IUI #1 or #2.

Whether or it not it's a waste of time probably depends on multiple factors, including age, financial / insurance situation, and root cause of fertility issues.

Anonymous wrote:

Anonymous wrote:Side note: how do doctors avoid the high order multiples that can happen with IUI? Like how the heck did the doctor allow this woman to proceed with trigger? (quintuplets)

http://people.com/human-interest/couple-pregnant-quintuplets-struggling-conceive/

Mine did ultrasounds before allowing the IUI and trigger to go forward. They wanted to see no more than 2 eggs I believe. If you got something like 8 eggs, they wouldn't do the IUI that cycle. I was afraid of twins as a petite person.

FWIW most of the twin moms I know got them from IUI and not IVF, or even worse- unmonitored Clomid. It's a common misconception that IVF gives twins.

This happened to me and I converted to an iVf cycle and that’s how I had my DD. I had 11 large follicales and they retrieved 9 eggs.

We had four failed IUIs (two with Clomid and two with injectables). Then we moved on to natural cycle IVF and it worked the first try. Unexplained infertility. Started TTC when I was 27 and then got pregnant just before I turned 34.

Anonymous wrote:Friends of ours got pregnant on their first IUI cycle. Their baby is 16 months old now. They just found out they are expecting their second baby, and didn't need IUI the second time.

This is so common and is what happened to us. We tried for 3 years for our first child, then we did IUI which worked. For the second child we only needed to try for 6 months before we were pregnant naturally. I could tell after pregnancy and breastfeeding that my cycles and hormones were in a much better place. I'd had PCOS before, but no longer had PCOS after pregnancy/breastfeeding.

I did 6 IUIs, all of them failed. Obviously in hindsight I could say it was a waste. But for us, it was much easier to spend $1500 on an IUI than to stare down the $25k price tag of IVF for ONE shot. We probably should have stopped after 3. I responded well to clomid, even had 5 follicles one cycle, and still nothing.

I did have a 2nd RE look over my results while we were researching IVF. He could not believe the first RE let me trigger and inseminate with the 5 follicles. Clearly, the cycle still failed, but it did make me nervous.

I got pregnant naturally (after 3 years of TI/IUI) the month before starting IVF. I believe I had endometriosis and that pregnancy made it better because I got pregnant very quickly three more time (1 mc, 1 chemical, 1 baby) while trying for my 2nd. Got pregnant in July, October and January (which stuck). That was crazy to me since it'd taken me three years with my first.

Have two healthy kids now.

Anonymous wrote:

Anonymous wrote:Unexplained infertility for me in my late 20s. Everything looked fine, but I had not conceived after trying for one year.

I got pregnant on the 5th try with IUI. The 5th one was different from the first 4 because: 1) my clomid dose was a quarter of the previous doses(I was incredibly sensitive to clomid and would ovulate 8 eggs on every try, and 2) they used some kind of curved/not frequently used catheter; I can't remember why.

wow, did they let you go forward with IUI when you had 8 eggs? and did you skip months between your IUIs?

They refused for the first one, told me that they would perform "selective reduction" for the second one if I was pregnant with too many. No pregnancy even with that many eggs.

I had 3 " ready-to-go"eggs on the 5th one, and still got pregnant with only one. My body is pretty messed up for some reason. (carried my baby to full term and she was born in the 3rd percentile for both height and weight-she is above the 95th percentile for both at age 5).

I skipped several months between some of them, but I can't remember much. The 5th one was about 5 months after the 4th.

Friends of ours got pregnant on their first IUI cycle. Their baby is 16 months old now. They just found out they are expecting their second baby, and didn't need IUI the second time.

Yes. I took Clomid each month, too; and did 3 or so months of Clomid without an IUI. We had success with the 3rd IUI.

I did it 3 times and got pregnant on my 1st IVF cycle. I wanted to go straight to IVF because the success rate for people with my stats is so high. Husband wanted to do IUI because that’s what the RE recommended.

Anonymous wrote:I did it for my first. Worked on the 3rd try. First two trys, I just used clomid. Third try, I did injectables.

I did it because it's way less invasive. And cheaper. I was prepared to move on to IVF after three rounds.

For my second, I went straight to IVF and did all single embryo transfers because I didn't want to risk multiples. Which ended up being a very arduous process, but ultimately worked out for me and I have no regrets.

How many kids did you end up having?

Anonymous wrote:Side note: how do doctors avoid the high order multiples that can happen with IUI? Like how the heck did the doctor allow this woman to proceed with trigger? (quintuplets)

http://people.com/human-interest/couple-pregnant-quintuplets-struggling-conceive/

Mine did ultrasounds before allowing the IUI and trigger to go forward. They wanted to see no more than 2 eggs I believe. If you got something like 8 eggs, they wouldn't do the IUI that cycle. I was afraid of twins as a petite person.

FWIW most of the twin moms I know got them from IUI and not IVF, or even worse- unmonitored Clomid. It's a common misconception that IVF gives twins.