I do a beef stew in our slow cooker. It's a bit of work at the beginning because I coat the meat cubes in seasoned flour, then brown in oil on the slow. The rest is simple though:
dump the browned beef cubes into the crockpot with 1 cup beef broth, 1 cup red wine, rosemary, thyme and garlic. Add sliced raw onions, potatoes, celery and carrots. Simmer all day and serve.