Anonymous wrote:

Anonymous wrote:My mother is 87 and has had major depressive episodes her whole adult life, but once antidepressants (SSRIs) became widely available she stayed well for very long stretches. But now that she's become elderly the major depression and extreme anxiety is back and is driving all of the declines in her health. An episode in 2022 lasted 10 months...she lost 40+ pounds, stopped driving and moved into a senior living facility, which finally broke the depression and she became her usual self again. Now we're 6 month in to another episode and nothing is helping. She had insomnia, but 3 months ago she started sleeping well again...but her anxiety and depression are as terrible as they ever have been. We've been trying everything - SSRIs, therapy, exercise/physical therapy - while treating all the physical health symptoms that one after another turn out to be caused by her anxiety/depression, such as issues swallowing/eating, tremors, weakness, etc. She doesn't have dementia although at this rate she's going to ruin her health until everything starts shutting down. Her physical health has always been good...she only takes medication for her blood pressure and assorted vitamin supplements (vitamin D, B vitamins, magnesium) and famotidine for reflux and occasionally takes Nexium for short periods when her anxiety makes the reflux a lot worse.

Please let me know if you have dealt with this with your elderly parents. Our family, especially my siblings, are continuously stressed out and are getting to the point where we are getting very angry at all of this self-inflicted misery. We have some childhood/young adult trauma from dealing with my mother's depressive episodes as well.

Does anyone have any recommendations for what to do when medications stop working? I've read about everything from TMS (transcranial magnetic stimulation) to electroshock therapy to esketamine (ketamine nasal spray)...but I'm not sure if any of this makes sense at her age. She honestly is likely to die from depression if we can't find a solution, but increasingly I'm wondering if that is the solution since she seems to be so invested in it. She actually is not suicidal - I think a lot of this is anxiety about aging and dying - but honestly the end result IS going to be dying if we can't break this cycle.

The end result is dying for everyone, depressed or not. Your mom has already lived a good long life that will end soon. Her kids have done well by her. Maybe you'll be lucky and be both undepressed and long lived.

Anonymous wrote:My mother is 87 and has had major depressive episodes her whole adult life, but once antidepressants (SSRIs) became widely available she stayed well for very long stretches. But now that she's become elderly the major depression and extreme anxiety is back and is driving all of the declines in her health. An episode in 2022 lasted 10 months...she lost 40+ pounds, stopped driving and moved into a senior living facility, which finally broke the depression and she became her usual self again. Now we're 6 month in to another episode and nothing is helping. She had insomnia, but 3 months ago she started sleeping well again...but her anxiety and depression are as terrible as they ever have been. We've been trying everything - SSRIs, therapy, exercise/physical therapy - while treating all the physical health symptoms that one after another turn out to be caused by her anxiety/depression, such as issues swallowing/eating, tremors, weakness, etc. She doesn't have dementia although at this rate she's going to ruin her health until everything starts shutting down. Her physical health has always been good...she only takes medication for her blood pressure and assorted vitamin supplements (vitamin D, B vitamins, magnesium) and famotidine for reflux and occasionally takes Nexium for short periods when her anxiety makes the reflux a lot worse.

Please let me know if you have dealt with this with your elderly parents. Our family, especially my siblings, are continuously stressed out and are getting to the point where we are getting very angry at all of this self-inflicted misery. We have some childhood/young adult trauma from dealing with my mother's depressive episodes as well.

Does anyone have any recommendations for what to do when medications stop working? I've read about everything from TMS (transcranial magnetic stimulation) to electroshock therapy to esketamine (ketamine nasal spray)...but I'm not sure if any of this makes sense at her age. She honestly is likely to die from depression if we can't find a solution, but increasingly I'm wondering if that is the solution since she seems to be so invested in it. She actually is not suicidal - I think a lot of this is anxiety about aging and dying - but honestly the end result IS going to be dying if we can't break this cycle.

Anonymous wrote:My mother is 87 and has had major depressive episodes her whole adult life, but once antidepressants (SSRIs) became widely available she stayed well for very long stretches. But now that she's become elderly the major depression and extreme anxiety is back and is driving all of the declines in her health. An episode in 2022 lasted 10 months...she lost 40+ pounds, stopped driving and moved into a senior living facility, which finally broke the depression and she became her usual self again. Now we're 6 month in to another episode and nothing is helping. She had insomnia, but 3 months ago she started sleeping well again...but her anxiety and depression are as terrible as they ever have been. We've been trying everything - SSRIs, therapy, exercise/physical therapy - while treating all the physical health symptoms that one after another turn out to be caused by her anxiety/depression, such as issues swallowing/eating, tremors, weakness, etc. She doesn't have dementia although at this rate she's going to ruin her health until everything starts shutting down. Her physical health has always been good...she only takes medication for her blood pressure and assorted vitamin supplements (vitamin D, B vitamins, magnesium) and famotidine for reflux and occasionally takes Nexium for short periods when her anxiety makes the reflux a lot worse.

Please let me know if you have dealt with this with your elderly parents. Our family, especially my siblings, are continuously stressed out and are getting to the point where we are getting very angry at all of this self-inflicted misery. We have some childhood/young adult trauma from dealing with my mother's depressive episodes as well.

Does anyone have any recommendations for what to do when medications stop working? I've read about everything from TMS (transcranial magnetic stimulation) to electroshock therapy to esketamine (ketamine nasal spray)...but I'm not sure if any of this makes sense at her age. She honestly is likely to die from depression if we can't find a solution, but increasingly I'm wondering if that is the solution since she seems to be so invested in it. She actually is not suicidal - I think a lot of this is anxiety about aging and dying - but honestly the end result IS going to be dying if we can't break this cycle.

Anonymous wrote:That's fantastic news!

Anonymous wrote:She got better when your sibling cut her off????

There's a message there. Step back. This is codependency you have going on. She's miserable, gets attention. Try dropping the rope.

Anonymous wrote:

Anonymous wrote:

If this is the best you can do, maybe you all need to take a step back and let paid caregivers be more primary in her life. Shaming her for being unable to “shake” a lifelong mental health condition is not going to work. It is especially not going to work when the threat is “or you will die”; she is 87 and will be dying regardless.

If the benzodiazepine was working, she could consider going back on it. Elevated ammonia in someone who is 87 is not like elevated ammonia in a 47 year old. Cutting her off from treatments that worked for the benefit of her long-term health is insane. She is 87; there is no long term.

Have you gotten treatment for your trauma? It sounds like you could use it. Good thoughts to you.

Her potential death from mental illness isn't a threat, it's a fact. She is aware and acknowledges that nearly all her decline in the past 5 years of so is because of her mental health problems. Rather than threatening what we are doing is telling her the consequences we are observing. It's a last plea for her to have some agency in her recovery, if she still has it in her.

Stepping back will just trigger further downward spirals. Now she's calling me telling me she's frightened and begging me to come over. We're refusing to come over more than once per day. She's also not in assisted living so there's no paid caregiver to depend on, though that may come in the near future.

The benzodiazepines are not coming back, because they increase the risk of falls and cognitive impairment and also increase the likelihood of high ammonia levels. Have you ever seen an elderly woman with high ammonia levels? In my mom she went from being her normal self to within 2 weeks not sleeping at all, having major tremors, being confused and disoriented with red-rimmed eyes and looking terrified...it is the worst state I have ever seen her in. It's a neurotoxin with major neurological symptoms that are way worse than the anxiety and depression.

If my mom could shake the anxiety and depression she could absolutely live another 10-15 yrs...she has had many relatives live between 95-99 yrs old. It's absolutely not worth it if she remains in her currently state, but I'm not exactly ready to leave her to die now (since you're concerned about my trauma!).