My wife works at a local hospital. She has an autoimmune disorder that forced her to get an organ transplant. She's back in the hospital and the kids are back at daycare. What else can we do really? She takes all the reasonable precautions, so we've pretty much decided it's not worth losing sleep over at this point. She's been dying in the ICU twice in her life already, so maybe we're just desensitized to it at this point.
Luckily, her particular type of autoimmune disorder doesn't seem to have particularly bad outcomes with COVID, so knowing that certainly helps. I'm sure it would be much more stressful if we didn't know that.
I think everyone knows this is an exceptional situation. I would hope people wouldn't be losing friends over this. In our case, we're actually in the more "liberal" camp when it comes to precautions, so we've actually had a chance to become better friends with some people.