Anonymous
Post 05/20/2018 18:18     Subject: How much would you pay to avoid a miscarriage?
I think you’re framing it too narrowly. Many abnormal embryos might simply fail to implant.
Anonymous
Post 05/20/2018 18:07     Subject: Re:How much would you pay to avoid a miscarriage?
Anonymous wrote:
Anonymous wrote:if PGS guaranteed no miscarriage yes. but it's more complicated than that. people miscarry PGS normals all the time. at the same time, there is evidence that some PGS abnormals self-correct. i think doctors just don't know enough about PGS yet.


There is no guarantee in anything IVF related, even with donor eggs. You are just trying to increase the chances of success and PGS testing gives you just that.


thanks for the lecture. personally I wouldn't pay so much and take additional risks (false alarm, damage to embryo) to merely increase my chances.
Anonymous
Post 05/19/2018 21:25     Subject: Re:How much would you pay to avoid a miscarriage?
Anonymous wrote:if PGS guaranteed no miscarriage yes. but it's more complicated than that. people miscarry PGS normals all the time. at the same time, there is evidence that some PGS abnormals self-correct. i think doctors just don't know enough about PGS yet.


There is no guarantee in anything IVF related, even with donor eggs. You are just trying to increase the chances of success and PGS testing gives you just that.
Anonymous
Post 05/19/2018 15:45     Subject: How much would you pay to avoid a miscarriage?
If I were in your position, OP, I’d follow the RE’s advice. Like PPs have said, PGS doesnt guarantee success, and the process slightly damages the embryos.
Good luck to you!
Anonymous
Post 05/19/2018 15:25     Subject: Re:How much would you pay to avoid a miscarriage?
My doc at SGF also recommended against PGS testing in our case. I was on the fence about it but he wasn't convinced it would help us so we are going to skip it. Hopefully we don't regret it. I'm in my early 30s and he said if I were in my late 30s it would be a different conversation. However, like the pp said, if it was a 100% guarantee of no miscarriage I would shell out the cash for it no question.
Anonymous
Post 05/16/2018 08:31     Subject: Re:How much would you pay to avoid a miscarriage?
if PGS guaranteed no miscarriage yes. but it's more complicated than that. people miscarry PGS normals all the time. at the same time, there is evidence that some PGS abnormals self-correct. i think doctors just don't know enough about PGS yet.
Anonymous
Post 05/15/2018 22:54     Subject: Re:How much would you pay to avoid a miscarriage?
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:We paid for it out of pocket. The price was set $3500 for up to 8 embryos. We only ever got 4 and all tested abnormal. Was it worth it? Emotionally absolutely yes if it kept me from having a miscarriage. The FET would have been $2600 or so. So I paid $1000 to save myself a lot of pain. Yes. Worth it.


I'm sorry to hear this. What are your next steps?


Bumping this thread with an update from me since I know so many of us are struggling with this decision. On my third round of IVF we got 5 embryos and froze them on Day 3. We decided not to do PGS this time. We did a FET with 2 of the untested embryos. I got pregnant but miscarried at 7 weeks. Now prepping to transfer the remaining 3. If that fails I have no idea what to do next.


I'm sorry. This process is such a beat down.
Anonymous
Post 05/15/2018 18:13     Subject: Re:How much would you pay to avoid a miscarriage?
Anonymous wrote:
Anonymous wrote:We paid for it out of pocket. The price was set $3500 for up to 8 embryos. We only ever got 4 and all tested abnormal. Was it worth it? Emotionally absolutely yes if it kept me from having a miscarriage. The FET would have been $2600 or so. So I paid $1000 to save myself a lot of pain. Yes. Worth it.


I'm sorry to hear this. What are your next steps?


Bumping this thread with an update from me since I know so many of us are struggling with this decision. On my third round of IVF we got 5 embryos and froze them on Day 3. We decided not to do PGS this time. We did a FET with 2 of the untested embryos. I got pregnant but miscarried at 7 weeks. Now prepping to transfer the remaining 3. If that fails I have no idea what to do next.
Anonymous
Post 04/11/2018 11:57     Subject: How much would you pay to avoid a miscarriage?
PGS does not rule out miscarriage. I had 4 chemical pregnancies with PGS embryos.
Anonymous
Post 04/11/2018 11:14     Subject: Re:How much would you pay to avoid a miscarriage?
Anonymous wrote:We paid for it out of pocket. The price was set $3500 for up to 8 embryos. We only ever got 4 and all tested abnormal. Was it worth it? Emotionally absolutely yes if it kept me from having a miscarriage. The FET would have been $2600 or so. So I paid $1000 to save myself a lot of pain. Yes. Worth it.


I'm sorry to hear this. What are your next steps?
Anonymous
Post 04/11/2018 10:51     Subject: How much would you pay to avoid a miscarriage?
Anonymous wrote:We paid for it out of pocket. Had previously frozen embryos thawed and tested. I'm currently miscarrying the first of our PGS normal embryos.
It is NOT a silver bullet against miscarriage. It lowers the odds, but they aren't zero.
Background info: I've never had a miscarriage before. One successful pregnancy/DC from a previous IVF cycle.


I’m so sorry.
Anonymous
Post 04/11/2018 10:42     Subject: How much would you pay to avoid a miscarriage?
We paid for it out of pocket. Had previously frozen embryos thawed and tested. I'm currently miscarrying the first of our PGS normal embryos.
It is NOT a silver bullet against miscarriage. It lowers the odds, but they aren't zero.
Background info: I've never had a miscarriage before. One successful pregnancy/DC from a previous IVF cycle.
Anonymous
Post 04/10/2018 22:19     Subject: Re:How much would you pay to avoid a miscarriage?
We paid for it out of pocket. The price was set $3500 for up to 8 embryos. We only ever got 4 and all tested abnormal. Was it worth it? Emotionally absolutely yes if it kept me from having a miscarriage. The FET would have been $2600 or so. So I paid $1000 to save myself a lot of pain. Yes. Worth it.
Anonymous
Post 04/10/2018 21:40     Subject: Re:How much would you pay to avoid a miscarriage?
I definitely think it's worth it. It doesn't cost that much more than a FET, right? About 4 k for PGS of 8 embryos (which you have 9 months to accumulate and send separately) vs 2500 for an FET. It's not a sure thing, but if you get to skip two failed transfers it would be worth it.

I should say that I sent 4 embryos for PGS and my 4AA was normal and my 3 3BBs were abnormal so I'm not totally convinced that you can't tell, to some extent, based on embryo grading (though everyone says it's not correlated)
Anonymous
Post 04/10/2018 19:40     Subject: Re:How much would you pay to avoid a miscarriage?
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:
Anonymous wrote:It was worth it for me to significantly lower the risk of miscarriage. Unfortunately, it does not rule out miscarriage and there have been several postings of women on this board that have miscarried PGS embryos. Putting aside the emotional cost of miscarriage, there are huge time sucks and set you back months in IVF. I'm surprised to hear your RE advised against it - mine at SGF and my OB at VHC - STRONGLY encourage it ( I was 34 w/PCOS). Was it discouraged specifically for you because of your DOR, or does the RE discourage it across the board? If it's the latter, that sounds usual and I'd suggest a second opinion.


She said it's only recommended for patients over 40 or people with recurrent miscarriages. To be fair, I've never had a miscarriage and I have 2 kids (one IVF, one miracle baby). But the thought of having a miscarriage from an untested embryo (I have one) kind of terrifies me.


If you are 35 and have already had two kids, one without medical intervention, you do not have severe DOR. Just do IVF and transfer what you get.


0.3 AMH and AFC of 3 isn't DOR?


My RE and I consider it severe DOR (those are my numbers, too).


A DOR diagnosis is usually a combination of your numbers and having tried IVF and had no or very little response to stimulation medicine. The OP might have DOR but since her last round led to 4 eggs being retrieved, it wouldn’t qualify. Now, that was a few years ago so her response might be much worse now. In that case, a cycle where she fails to respond to stimulation would give her a more accurate diagnosis. I would do at least one new round to see how the response is before deciding that PGS is worth it.