Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Another troll trying to take advantage of patents of SN children.
DP. Doesn’t sound like a troll to me. Look at the research links.
What's trolly about it is the huge claim "75% of autistic people" with no cite. Best I can tell, there is a study that found 75% of the 93 study participants had it, and a minority of them had some improvement during the treatment.
The NIH study linked here said ONE-THIRD of the 93 children treated with leucovorin showed MODERATE to MUCH IMPROVEMENT.
“ Compared with controls, significantly higher improvement ratings were observed in treated children over a mean period of 4 months in verbal communication, receptive and expressive language, attention and stereotypical behavior. Approximately one-third of treated children demonstrated moderate to much improvement. The incidence of adverse effects was low. This study suggests that FRAs may be important in ASD and that FRA-positive children with ASD may benefit from leucovorin calcium treatment”
Anonymous wrote:Another troll trying to take advantage of patents of SN children.
Anonymous wrote:Anonymous wrote:Anonymous wrote:Another troll trying to take advantage of patents of SN children.
DP. Doesn’t sound like a troll to me. Look at the research links.
What's trolly about it is the huge claim "75% of autistic people" with no cite. Best I can tell, there is a study that found 75% of the 93 study participants had it, and a minority of them had some improvement during the treatment.
Anonymous wrote:Anonymous wrote:Another troll trying to take advantage of patents of SN children.
DP. Doesn’t sound like a troll to me. Look at the research links.
Anonymous wrote:Just sharing a win!
Ds (level1) has been on leucovorin for about 3 months now.
We've noticed so many small improvements in engagement, mood, conversation but the best one has to be the smiles!
Today he came to show us something and had completely normall eye contact and the biggest, most beautiful smile the whole time! My heart is FULL!!!
Anonymous wrote:Another troll trying to take advantage of patents of SN children.
Anonymous wrote:Just sharing a win!
Ds (level1) has been on leucovorin for about 3 months now.
We've noticed so many small improvements in engagement, mood, conversation but the best one has to be the smiles!
Today he came to show us something and had completely normall eye contact and the biggest, most beautiful smile the whole time! My heart is FULL!!!
Anonymous wrote:Anonymous wrote:Anonymous wrote:You write like a spammer and you aren't providing the information people actually need. That's why people ignore you. It's not because they're burned out (though they are). It's because you aren't persuasive. You sound like you're trying to sell essential oils.
For anyone who would actually like to read real studies:
https://pmc.ncbi.nlm.nih.gov/articles/PMC7477301/
https://www.nejm.org/doi/full/10.1056/NEJMoa043160
https://pmc.ncbi.nlm.nih.gov/articles/PMC3578948/
Pound sand. Pp. It was a parent sharing a success which is much more readable than a bunch of link drops that have zero relationship with actual autism parenting. But thanks a sh!t ton for "Cerebral folate deficiency (CFD) syndrome is a recently described neurometabolic disorder characterized by low concentrations of 5-methyltetrahydrofolate (5MTHF) in the cerebrospinal fluid (CSF), despite normal systemic folate levels. CFD is believed to be caused by the impaired transport of folates across the blood–brain barrier. The first reported cases of CFD manifested severe neurodevelopmental symptoms including spastic paraplegia, cerebellar ataxia, dyskinesia, seizures, acquired microcephaly and developmental regression, which occurred as early as 4 months of age.1, 2 Central visual disturbances (optic atrophy and blindness) and hearing loss occurred after age 3 and 6 years, respectively, in some cases.2"
Et, al! Lmao
Personally I find that a lot more helpful than "Omg so smiley! THEY mystery they have found..."
Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Anonymous wrote:Why is he on it?
They have found that 75% of autistic people have an underlying immune condition where their bodies mistakenly create antibodies thatbattack the folate receptors. This results in a folaye deficiency in the brain. * The brain needs folate to function properly.
Since a huge majority of autistic people have this underlying condition, every autistic person should be tested for this.
* please note that a regular serum folate tesr does NOT show folate deficiency because this is not caused by lack of ingesting enough folate. The problem occurs when the body tries to transport that folate across the blood- brain barrier. Those specific folate receptors are comprised and can't do their job. So blood test is fine but if you did a spinal tap you would find low levels of folate in the spinal fluid. Obviously they dont want to do such an invasive procedure, so Dr Quadros devised a test to look for and measure the auto antibodies. If the antibodies exist you can reasonably assume there is a lack of folate in the nervous system/brain
Please share a citation and explain who "they" are.
Why are people like you so awful? Its obvious "they" are the researchers that op wrote about. And there were numerous descriptions of where to find more information if you would like citations.
Oh where were these numerous descriptions? OP name-checked one researcher, that's it, so I found some stuff by googling.
OP complained that people don't follow up. But they don't follow up because OP isn't providing the information and OP's tone is spammy, like she's trying to draw attention before making a sales pitch.
Anonymous wrote:Anonymous wrote:You write like a spammer and you aren't providing the information people actually need. That's why people ignore you. It's not because they're burned out (though they are). It's because you aren't persuasive. You sound like you're trying to sell essential oils.
For anyone who would actually like to read real studies:
https://pmc.ncbi.nlm.nih.gov/articles/PMC7477301/
https://www.nejm.org/doi/full/10.1056/NEJMoa043160
https://pmc.ncbi.nlm.nih.gov/articles/PMC3578948/
Pound sand. Pp. It was a parent sharing a success which is much more readable than a bunch of link drops that have zero relationship with actual autism parenting. But thanks a sh!t ton for "Cerebral folate deficiency (CFD) syndrome is a recently described neurometabolic disorder characterized by low concentrations of 5-methyltetrahydrofolate (5MTHF) in the cerebrospinal fluid (CSF), despite normal systemic folate levels. CFD is believed to be caused by the impaired transport of folates across the blood–brain barrier. The first reported cases of CFD manifested severe neurodevelopmental symptoms including spastic paraplegia, cerebellar ataxia, dyskinesia, seizures, acquired microcephaly and developmental regression, which occurred as early as 4 months of age.1, 2 Central visual disturbances (optic atrophy and blindness) and hearing loss occurred after age 3 and 6 years, respectively, in some cases.2"
Et, al! Lmao