Anonymous
Post 06/02/2025 12:31     Subject: microdosing GLPs?
Anonymous wrote:
Anonymous wrote:I lost 22 pounds in 4 months, never going above 0.75mg compounded Semaglutide (max dosage is 2.4mg). I’m now on 0.5mg for 4 weeks, then down to 0.25mg through Christmas. I’ve had occasional constipation but no other side effects. It was a very smooth process and I feel great.

I think being in that 10-20lb range is the hardest mentally because you’re still close enough to your old size that you can squeeze into your clothes but everything is uncomfortable. You look at pictures and see a roll where there never was before. I can’t tell you how much my self esteem has improved just by not being pinched wearing my shorts from just 2 summers ago.


This makes me feel so much better thank you and I think you understand exactly where I’m coming from. I see my reflection in the office glass and I can’t believe it’s my body. It’s like my bottom has migrated up to my back with back fold and cleavage and I’m repulsed by myself. And exactly, I have like two pairs of pants that I can fit into that were always my fat pants and now I’m starting to bulge out of them. I love my clothes and it kills me that I can’t fit into any of them. This gives me hope that you are on such low doses, not to be graphic , but I have a fast digestive system and my day-to-day normal is diarrhea several times a day. Yes I have already had a colonoscopy. So the idea of slowing down my digestive system isn’t entirely a bad thing.


One of the big things for me is that I completely lost my taste for alcohol. I may choke down a glass of champagne at a wedding, but I’ve gone weeks without any desire to drink. That in turn meant sleeping better, more energy in the gym, less brain fog.

I’ve tracked my weight for years and I always went up 5-10lbs in Oct-Dec with football Sundays and the holidays. I want to stay on a minimal dose until Christmas just to help with building habits (especially knowing I can attend parties and activities without eating constantly and drinking, and also getting comfortable with telling people “I’m not drinking” without explaining myself).

I was originally sort of a naysayer, but it’s truly been life changing and done a lot for me mentally and physically.
Anonymous
Post 06/01/2025 22:47     Subject: microdosing GLPs?
Anonymous wrote:PP but I don't think your chubby comment was judgmental. To me, it implied that the doctor doesn't see the issue with HER OWN body (rightly so) but that might prevent her from understanding how much impact PP's relative weight gain is to PP's body and self-esteem.


Yes. Judgy. Like the spin instructor who called me chunky at the gym.
Anonymous
Post 06/01/2025 22:29     Subject: microdosing GLPs?
I am taking .25 and it’s been transformational beyond weight loss.

I’ve lost the 7-10 pounds I rapidly gained when perimenopause symptoms ramped up. I also developed a severe sodium sensitivity that would cause major bloating and swelling. Somehow that disappeared along with aches and pains I assume we’re peri related too.
Anonymous
Post 06/01/2025 12:26     Subject: microdosing GLPs?
Anonymous wrote:I lost 22 pounds in 4 months, never going above 0.75mg compounded Semaglutide (max dosage is 2.4mg). I’m now on 0.5mg for 4 weeks, then down to 0.25mg through Christmas. I’ve had occasional constipation but no other side effects. It was a very smooth process and I feel great.

I think being in that 10-20lb range is the hardest mentally because you’re still close enough to your old size that you can squeeze into your clothes but everything is uncomfortable. You look at pictures and see a roll where there never was before. I can’t tell you how much my self esteem has improved just by not being pinched wearing my shorts from just 2 summers ago.


This makes me feel so much better thank you and I think you understand exactly where I’m coming from. I see my reflection in the office glass and I can’t believe it’s my body. It’s like my bottom has migrated up to my back with back fold and cleavage and I’m repulsed by myself. And exactly, I have like two pairs of pants that I can fit into that were always my fat pants and now I’m starting to bulge out of them. I love my clothes and it kills me that I can’t fit into any of them. This gives me hope that you are on such low doses, not to be graphic , but I have a fast digestive system and my day-to-day normal is diarrhea several times a day. Yes I have already had a colonoscopy. So the idea of slowing down my digestive system isn’t entirely a bad thing.
Anonymous
Post 06/01/2025 11:55     Subject: microdosing GLPs?
I lost 22 pounds in 4 months, never going above 0.75mg compounded Semaglutide (max dosage is 2.4mg). I’m now on 0.5mg for 4 weeks, then down to 0.25mg through Christmas. I’ve had occasional constipation but no other side effects. It was a very smooth process and I feel great.

I think being in that 10-20lb range is the hardest mentally because you’re still close enough to your old size that you can squeeze into your clothes but everything is uncomfortable. You look at pictures and see a roll where there never was before. I can’t tell you how much my self esteem has improved just by not being pinched wearing my shorts from just 2 summers ago.
Anonymous
Post 06/01/2025 10:59     Subject: microdosing GLPs?
Consistent exercise not coffee whoops
Anonymous
Post 06/01/2025 10:55     Subject: microdosing GLPs?
This will be me pp micro dosing. Starting today and feel depressed, scarred, and hopefull. It makes me sick that I may be on a medication for the rest of my life, currently not on any, but the extra 15 lbs compounded my dumpster fire of a life (mainly partner’s unemployment and mental health crisis) leaves little alternative. I have no time for coffee sister exercise and my friends and d willl power varies day to day. People do you treat you differently when you gain weight and it’s been tough.
Anonymous
Post 05/31/2025 08:58     Subject: microdosing GLPs?
I have been microdosing tirzepatide. Got it from MIDI. I started with 0.5 mg which is 1/5 of the smallest recommended doze. Worked through some GI side effects. I wanted to try it mostly to improve sleep. It’s been studied now for many other applications including anti inflammatory, help with menopause symptoms, and many others.
I got to 2.5 mg and not planning to go above it. Possibly reduce to half of that amount. I only lost 2-3 pounds and I know that the moment you stop it all comes back.
So, as far as I’m concerned there isn’t an exit solution for GLP-1 drugs. You stay on it and keep paying forever or you stop.
I think it help a bit with my sleep.
Anonymous
Post 05/31/2025 00:36     Subject: microdosing GLPs?
Anonymous wrote:Thank you for asking PP. I did have pretty thorough bloodwork but really in this day and age. What does that mean? I feel like when you are a certain age doesn’t matter if your doctor is male or female you’re just written off. So who knows there could be something more extensive wrong but Going from one specialist to the next only to be ricocheted all around while I get fatter and more depressed isn’t doable.


I agree
-a poster from page 1
Anonymous
Post 05/31/2025 00:20     Subject: microdosing GLPs?
Anonymous wrote:Oh the protein b..tch. Thanks if only I just had more protein, of course. .


Wow if GLPs make you this happy, I can’t wait to try them…
Anonymous
Post 05/30/2025 21:35     Subject: microdosing GLPs?
Thank you for asking PP. I did have pretty thorough bloodwork but really in this day and age. What does that mean? I feel like when you are a certain age doesn’t matter if your doctor is male or female you’re just written off. So who knows there could be something more extensive wrong but Going from one specialist to the next only to be ricocheted all around while I get fatter and more depressed isn’t doable.
Anonymous
Post 05/30/2025 21:08     Subject: microdosing GLPs?
Anonymous wrote:
Anonymous wrote:PP but I don't think your chubby comment was judgmental. To me, it implied that the doctor doesn't see the issue with HER OWN body (rightly so) but that might prevent her from understanding how much impact PP's relative weight gain is to PP's body and self-esteem.


Thank you yes that’s what I was getting at. And to the other pp, judge away but know that you are making assumptions about me and my circumstances-son just diagnosed with a brutal syndrome, I started a new job, partner lost theirs and is having a mental health crisis and suffered a a brain injury that now prevents them from driving, Meanwhile, I have one pair of pants I can fit into. Going the ozempic route is for mental health and my wallet. Can’t afford new work cloths I’m in the office everyday fyi. Even when I was running 30 miles a week there was weight that would not come off. Do t have the time or energy for that kind of exercise now


I'm really sorry you're going through this. Did the doctor do extended bloodwork? Because you could be hypothyroid and this could be the cause of your weight gain.
Anonymous
Post 05/30/2025 20:39     Subject: microdosing GLPs?
Oh the protein b..tch. Thanks if only I just had more protein, of course. .
Anonymous
Post 05/30/2025 03:04     Subject: microdosing GLPs?
Anonymous wrote:I am starting to try it. I gained 15lbs due to thyroid problems and peri-menopause. I am a daily exerciser and lift heavy. Was eating and doing everything the same as I did during my 40s but at 50, weight started piling on. I have been on wegovy since November and now at my goal weight. I got up to the 1.7 dose. I am staying at that dose but injecting every two weeks instead of weekly. If my weight continues to decline, I’ll try every three weeks.

I do think this is a medication for life. Everyone knows what they need to do to lose weight so it isn’t about educating yourself on what is the appropriate amount to eat. Wegovy just stops you thinking about food. At 52, I don’t need as much food as I used to need. Sadly my body still wants to eat the same amount.


I think many of us (myself included) can eat more esp fat and protein and not feel hungry and lose weight. It was a shock to me but true when I got serious about eating more than 100 grams protein a day to try to help PeriM symptoms not to lose weight. I eat more now than I did in my 30s bc of protein and healthy fats like nuts seeds avocados. Wish I’d known better in my 30s bc I was always restricting/ trying salads and such.
Anonymous
Post 05/30/2025 01:04     Subject: microdosing GLPs?
I am starting to try it. I gained 15lbs due to thyroid problems and peri-menopause. I am a daily exerciser and lift heavy. Was eating and doing everything the same as I did during my 40s but at 50, weight started piling on. I have been on wegovy since November and now at my goal weight. I got up to the 1.7 dose. I am staying at that dose but injecting every two weeks instead of weekly. If my weight continues to decline, I’ll try every three weeks.

I do think this is a medication for life. Everyone knows what they need to do to lose weight so it isn’t about educating yourself on what is the appropriate amount to eat. Wegovy just stops you thinking about food. At 52, I don’t need as much food as I used to need. Sadly my body still wants to eat the same amount.