Real-World Effectiveness of Nirmatrelvir in Protecting Long COVID for Outpatient Adult Patients – A Large-Scale Observational Cohort Study from the RECOVER Initiative
https://pmc.ncbi.nlm.nih.gov/articles/PMC11213188/
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Paxlovid treatment was associated with a lower risk of incident Long COVID across systems as shown in Fig. 2D, including post-acute neurological conditions (sleep disorders, cognitive problems, headache, encephalopathy, dementia), post-acute pulmonary conditions (pulmonary fibrosis, acute pharyngitis, shortness of breath), post-acute blood conditions (anemia), post-acute metabolic conditions (edema, diabetes, malnutrition), post-acute digestive conditions (abdominal pain, constipation), post-acute musculoskeletal conditions (joint pain), and some general conditions in the post-acute phase (e.g., malaise and fatigue, fever, smell, and taste).
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Paxlovid treatment was also associated with a lower risk of incident Long COVID in different subpopulations stratified by sex, race, age, baseline risk conditions (except for pregnant females), infection time, and different rural-urban commuting areas as shown in Fig. 3.