You either should focus on Marriott brands (over 30 brands like Ritz Carlton, Fairfield, Spring Hill, courtyard, st Regis, etc.) or Hilton, which has things like Waldorf Astoria and Hampton inn. Hyatt and IHG are also parent brands but Marriott and Hilton are biggest of their kind in the us.

Also read The Points Guy or One Mile at a Time for how to maximize hotel points.