Try searching common sense media by age, platform, and multi player or real time:
https://www.commonsensemedia.org/game-reviews

OP - I'm looking for games that can be played interactively over the computer. My parents are in Florida.

Animal charades
Mad libs

Simon says

That party memory game. Have your parents put random items on a tray. The focus there camera on the items and let your kids look at them. They cover the camera, take one item away, then show the tray again to see if the kids can guess which item is gone.

Sing-along

I’m looking for on line games that my children can play with their grandparents in real time as a way to keep my kids busy and close to their GP’s. Any ideas? TIA.