Yes yes and yes. Took it for hyperemesis gravidarium during pregnancy. One should take colace or miralax when prescribed zofran.

Anonymous wrote:Yes. Back in the days where they gave this for pregnancy this happened to me.

They still give this for pregnancy, I'm on it right now.

I get horrible constipation from Zofran last 7-10 days after 24-48 hours of doses. Even worse when I’m taking the Zofran for the stomach flu (vice pregnancy), so I’m eating less and less fiber.

A few dried apricots, fresh apples as part of her diet along with the zofran should help plus extra fluid...water/lemonade/soup/ etc...

100% yes (and the lack of regular food with fiber just makes it worse). Next time, ask the ped about giving stool softeners (or at a minimum probiotics) to prevent this. It's tricky if you think diarrhea is going to follow the vomiting, but I would guess that if the vomiting has stopped and it's been 24 hours without diarrhea (or a normal BM) you probably need a stool softener because constipation is coming.

Holy cow, yes. Worst I’ve ever experienced. Good luck! I’m sorry your daughter is experiencing these two extremes. It isn’t fun.

Yes. Back in the days where they gave this for pregnancy this happened to me.

One of the listed side effects of zofran is constipation. Anyone ever have bad constipation show up several days later? DD had a couple doses of Zofran over the weekend and last night had serious constipation (like crying in pain, had to give her a glycerin suppository constipation, which I've never seen with any of my kids before). Not that it matters much - it's better than vomiting - but anyone had that happen days after taking Zofran? Wondering if it's related or if it's just that she hadn't eaten anything with fiber in 5 days.