Anonymous
Post 02/07/2019 21:18     Subject: It didn’t work again

Hi. I am so sorry. I went through something similar. First two donors resulted in a few blasts but I didn’t get pregnant or I had miscarriages. We did change my protocol multiple times and then we decided to give it one more try and do everything we could.. It was the third donor that finally worked.

Each cycle gave us more clues. I never got pregnant from a frozen embryo. I only got pregnant from fresh (I had one older child from my own eggs and a fresh cycle but nothing left to freeze.). I really started to assume right away that frozen would not work for me - I needed the fresh cycle which was one reason we went for that third try. For that third transfer I was also on steroids to do something for the immune system. Also took a lot of other meds. It was a long road and for sure a miracle.
Anonymous
Post 02/07/2019 16:30     Subject: Re:It didn’t work again

Thanks for the encouragement everyone. I’m just tired.

***sensitive miscarriage info***

We’re cruising in 2 days and I have not bled at all. I just found out Wed and they said they could do a D&C today but I opted not to do it and see if it will happen naturally. I’m still taking progesterone to see if I can at least make it through the cruise. I’ve has a couple miscarriages before very early like this so I know what to expect, but ugh I’m not even excited, but keeping it together for my son.
Anonymous
Post 02/07/2019 16:24     Subject: Re:It didn’t work again

We did tests on the sperm but it came back ok. I think there is something there too, but no other testing can be done.
Anonymous
Post 02/07/2019 15:44     Subject: It didn’t work again

Anonymous wrote:Sounds like a sperm issue. Has he had not just the sperm count but the deeper examination? They do genetic testing and see things like fragmentation.


I hit enter too soon
I say this because you had 4 embryos in 2 DE rounds, so out of 8 embryos only 1 made it to blast. That low with at least one proven donor—check the sperm.
Anonymous
Post 02/07/2019 15:41     Subject: It didn’t work again

Sounds like a sperm issue. Has he had not just the sperm count but the deeper examination? They do genetic testing and see things like fragmentation.
Anonymous
Post 02/07/2019 15:39     Subject: It didn’t work again

Keep your eye on the prize- stay the course!!!
Anonymous
Post 02/07/2019 15:27     Subject: Re:It didn’t work again

Anonymous wrote:The first donor was not proven, but the 2nd was. We had 7 frozen eggs from first, but only 5 thawed, 4 fertilized and then no blasts. 2nd had 5 frozen eggs, 4 thawed and fertilized, but only one blast.

As for me, I have no diagnoses. Everything looks good on paper. I would always get 10-12 eggs and 8-10 fertilize, but one cycle didn’t have a blast good enough to do testing and no transfer. The other 2 times I got 1 blast each so I said just xfer no testing but nothing implanted.

I though donor would be a sure thing, but maybe we need to look into adoption.



I get it about just being tired and disappointed and not hopeful. We were there; like you, secondary infertility. We adopted. Best thing we've ever done. Whatever you choose, OP, sending you hugs and good thoughts.
Anonymous
Post 02/07/2019 15:10     Subject: Re:It didn’t work again

Anonymous wrote:The first donor was not proven, but the 2nd was. We had 7 frozen eggs from first, but only 5 thawed, 4 fertilized and then no blasts. 2nd had 5 frozen eggs, 4 thawed and fertilized, but only one blast.

As for me, I have no diagnoses. Everything looks good on paper. I would always get 10-12 eggs and 8-10 fertilize, but one cycle didn’t have a blast good enough to do testing and no transfer. The other 2 times I got 1 blast each so I said just xfer no testing but nothing implanted.

I though donor would be a sure thing, but maybe we need to look into adoption.



First, I am so sorry you have gone through so much and I hope it works out for you. I am just beginning the DE process so I havent experienced it but I was told by my clinic (in PA) that fresh donor eggs have much better odds fo success than frozen. Have you talked to your doctor about the differences? Similarly, clinics are also finding that women who freeze their eggs with hopes to use them later in life are having trouble bc the eggs thaw well or once fertilized dont make it to blast.

I am really struggling with what to do. My clinic has 3 plans: one where you get all the egss from the retrieval (but its very expensive ), one plan where you split the proceeds of a retrieval with another anonymous family but you have to wait (could be months) for someone who wants to use the same donor as you, and lastly a plan where you can buy frozen eggs from their bank -- but I have been warned the odd of success is much lower.
Anonymous
Post 02/07/2019 14:55     Subject: It didn’t work again

If you're up for another cycle, you could discuss transferring an embryo on Day 2 or 3 pre-blast. Not all embryos can survive to Day 5. It worked for me.
Anonymous
Post 02/07/2019 14:42     Subject: Re:It didn’t work again

The first donor was not proven, but the 2nd was. We had 7 frozen eggs from first, but only 5 thawed, 4 fertilized and then no blasts. 2nd had 5 frozen eggs, 4 thawed and fertilized, but only one blast.

As for me, I have no diagnoses. Everything looks good on paper. I would always get 10-12 eggs and 8-10 fertilize, but one cycle didn’t have a blast good enough to do testing and no transfer. The other 2 times I got 1 blast each so I said just xfer no testing but nothing implanted.

I though donor would be a sure thing, but maybe we need to look into adoption.

Anonymous
Post 02/07/2019 12:14     Subject: Re:It didn’t work again

What’s your diagnosis?
Anonymous
Post 02/07/2019 11:42     Subject: It didn’t work again

So sorry op. The roller coaster ride is awful. I'm hoping it works out for you. Hugs.
Anonymous
Post 02/07/2019 11:39     Subject: Re:It didn’t work again

are these proven donors?
Anonymous
Post 02/07/2019 11:25     Subject: Re:It didn’t work again

Op here. That shouldn’t be a ?.
Anonymous
Post 02/07/2019 11:24     Subject: It didn’t work again

3 ivf with only one egg each. 2 transfers- no baby

One donor cycle with nothing to transfer
2nd donor cycle-new donor- 1 blast and got a bfp, but it was an empty sac.

If we try again, we have to pick another donor. I’m just so tired, but really want another?.