I have similar stats to you, OP. Got pregnant easily on my first try at 33, miscarried, pregnant again, miscarried, went to an RE and was diagnosed with DOR (AFC of 3 and undetectable AMH) but got pregnant naturally first month seeing RE. DD is 18 months now and we've been TTC since 10 months when I got my period back. My stats are the same and I have minimal hope of getting pregnant again (on the fence about even trying IVF). After my first miscarriage I was diagnosed with Hashimotos and my RE has a vague suspicion that the two are related -- perhaps an autoimmune disorder attacking my ovaries. He has no idea, really, but said he sees a lot of cases similar to mine and has a hunch that there's a relationship between the two.

Anonymous wrote:

Anonymous wrote:#1 conceived naturally at 29 after 7 cycles of TTC. Diagnosed with DOR at 32 after a year of unsuccessfully trying for #2. FSH or 5.59, I think AMH of .3 had no pregnancies at all in 18 months including with 3 medicated IUIs. First IVF finally got a BFP but it was a chemical. In the midst of second IVF currently (am now 33).

No clear family history that would explain it (that I'm aware of, at least). My RE has no idea why I have it. It's very frustrating. I am very sad about it because in a perfect world, I want three which is appearing less and less likely as time goes on. I am trying to focus on being grateful that I do have one child, because with this diagnosis I realize I could very well have zero kids.

Me again. I should add that it has taken me a long time to get to the place where I can say I'm sincerely trying this. Where you are, OP, four months in - I was still just plain angry at my situation even though anger of course isn't rational here. I still am angry, but also getting a little resigned to the situation out of necessity.

PP with mild DOR here. I'm still in the disbelief/anger stage and I've been TTC for 4 years unsuccessfully I have no idea how long it will take me to finally be at peace with the situation.

Anonymous wrote:#1 conceived naturally at 29 after 7 cycles of TTC. Diagnosed with DOR at 32 after a year of unsuccessfully trying for #2. FSH or 5.59, I think AMH of .3 had no pregnancies at all in 18 months including with 3 medicated IUIs. First IVF finally got a BFP but it was a chemical. In the midst of second IVF currently (am now 33).

No clear family history that would explain it (that I'm aware of, at least). My RE has no idea why I have it. It's very frustrating. I am very sad about it because in a perfect world, I want three which is appearing less and less likely as time goes on. I am trying to focus on being grateful that I do have one child, because with this diagnosis I realize I could very well have zero kids.

Me again. I should add that it has taken me a long time to get to the place where I can say I'm sincerely trying this. Where you are, OP, four months in - I was still just plain angry at my situation even though anger of course isn't rational here. I still am angry, but also getting a little resigned to the situation out of necessity.

#1 conceived naturally at 29 after 7 cycles of TTC. Diagnosed with DOR at 32 after a year of unsuccessfully trying for #2. FSH or 5.59, I think AMH of .3 had no pregnancies at all in 18 months including with 3 medicated IUIs. First IVF finally got a BFP but it was a chemical. In the midst of second IVF currently (am now 33).

No clear family history that would explain it (that I'm aware of, at least). My RE has no idea why I have it. It's very frustrating. I am very sad about it because in a perfect world, I want three which is appearing less and less likely as time goes on. I am trying to focus on being grateful that I do have one child, because with this diagnosis I realize I could very well have zero kids.

I had to have fertility treatments for #1 at 34, with an AMH of 0.6 - two years later I easily and naturally got pregnant with #2 ... go figure. In my case I wonder if it's genetic - my maternal grandmother didn't get her period until age 16, it took her over 4 years to get pregnant with my mom (her only pregnancy), and she was menopausal by 35. Not sure what her issues were since it was in a foreign country with subpar healthcare.

Sounds like you maybe got lucky withy your first.

I had <.01 AMH when I was 37. Had been trying for 1 year at that point, and had given birth to a naturally conceived child 2 years before. I ended up doing natural cycle ivf at Dominion and it worked the first time.

Maybe that's something to look into. I didn't want to do all of the drugs, and it was a lot cheaper than traditional IVF.

41-years-old. AMH 0.7. Produce 5-6 follicles on one ovary under stimulation. Produce only 1 follicle on another ovary due to 2.6 cm endometrioma that has engulfed part of the ovary. In my case, it is clear that it is ovarian endometriosis on one ovary. If it was not for that cyst I would have 5-6 follicles on an affected ovary too, under stimulation. As a result I have to go through number of banking cycles to get a good number of embryos. Endometriosis sucks, silent or non silent one.

PP here. My AMH and AFC has also stayed the same over 4 years but I have not been able to get pregnant.

My biggest question about DOR is why can't I get pregnant at all? I've had zero BFPs in 4 years, not even a chemical or miscarriage. I'm just wondering why my eggs are not fertilizing or implanting at all, even if they are not good quality eggs.

Anonymous wrote:About 4 months ago I was diagnosed with DOR - AMH was undetectable and FSH was 15. I am 36 and had a DD 2 years ago at 34 (got pregnant with her on the first try). DH and I started trying again when she was 1, and then after a year of nothing my OB finally sent me to an RE who ran all the tests.

I just don't understand how my stats can be so bad at my age and given the fact that I had no issues getting pregnant with my first so recently. I tried to get answers from my RE about possible reasons for my DOR, but she really has no clue. I don't have fragile X or any other genetic markers. Is there anything else that can lead to it at a younger age? I am really more curious than anything.

Anyone have thoughts?

DOR is a giant mystery. Some think it's "silent endometrosis". Some of it is genetic and who knows when your egg reserve takes a deep dive. I will say an FSH of 15 means that your body is working harder to turn out follicles (as my RE says, your body steps on the gas pedal when the end is getting nearer). Egg quantity does not equate with egg quality, though. BUt after age 35 the quality does go down.

Last year there was a huge study that showed that DOR actually has no effect on getting pregnant (for patients under 35). It does mean that you are less likely to respond to drugs.

There's a low amh/dor facebook group with a lot of information (some good, some not so good) if you want more info/input.

I tested with an 0.3 AMH at age 31. I'm almost 35 now and have the same AMH.

This is my story too. I got pregnant with my son on the first try at 35. Delivered at 36 and had a super easy, healthy pregnancy and delivery (no c-section). Started TTC #2 when he was 6 months old. Now he's almost 5 and I've never been pregnant again. I did 3 IUIs, 1 IVF, and had 2 surgeries, a lap and an operative hysteroscopy.

My numbers are very good but my AMH is low (.70). But not super low. My AFC is 10 (lowest recorded), my FSH is 5, and my estradiol is 42. All my other infertility tests are normal and no male factor. I did have 2 polyps in my uterus but had those removed, made no difference unfortunately.

I've had zero BFPs in almost 4 years. I am really shocked and saddened about this and don't understand why I can't get pregnant again.

I met with Cornell (DOR experts) and they told me I do not have DOR. Shady Grove said I'm just old (when I consulted there at 37).

About 4 months ago I was diagnosed with DOR - AMH was undetectable and FSH was 15. I am 36 and had a DD 2 years ago at 34 (got pregnant with her on the first try). DH and I started trying again when she was 1, and then after a year of nothing my OB finally sent me to an RE who ran all the tests.

I just don't understand how my stats can be so bad at my age and given the fact that I had no issues getting pregnant with my first so recently. I tried to get answers from my RE about possible reasons for my DOR, but she really has no clue. I don't have fragile X or any other genetic markers. Is there anything else that can lead to it at a younger age? I am really more curious than anything.

Anyone have thoughts?