Graco suggests mild liquid soap. I'd probably tip the thing onto its side (vomit side down) on top of a towel. Squirt some liquid soap on the area that got hit, blot and scrub as needed with a wet sponge or towel, then rinse with another wet sponge or towel.
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Vinyl, Plastic, and Metal Parts (mattress, mesh sides, frame)
Use a damp cloth or sponge with hand soap or dish soap to wipe clean the vinyl, plastic, and metal parts. Stay away from harsh household cleaners. Never use bleach to clean your Pack n' Play. If your Pack n' Play gets sandy, carefully remove all sand from all surfaces before packing it into the carry bag.
Carry Bag
Machine wash in cold water on the delicate cycle and drip dry.
Sheet
Pack N' Play playard sheets are fully machine washable, and can be drip-dried or tumble dried. Never use bleach to clean this product.
Soft Toys
Soft, cloth toys can be spot cleaned with warm soapy water. Be careful not to let water drip into the battery compartment!
Note: never use bleach to clean any part of this product.