Certainly. That is a very long flight, though, and you will probably want to allow for a very easy first day or so. Spend the first day or so in Tokyo and wander around to get a feel for it. That's the day to explore shops, etc.--take a nap and just enjoy the ambiance a little. After that, you can see the sights.
You cannot possibly see everything--I lived there for a year and there is so much I did not see. But, you can enjoy what you do see.