It's a big city. What do you enjoy? If you like art, perhaps the Philadelphia Museum of Art. Restaurants that are BYOB are a big Philly thing - make a reservation.
NY Times just did a 36 Hours in Philadelphia article with a lot of good recs:
http://www.nytimes.com/interactive/2016/05/26/travel/what-to-do-36-hours-in-philadelphia.html