One of my favorite restaurants (Roastfish and Cornbread) closed but the chef has opened a new place up back across in Bluffton called Burnin' Down South. Try it and report back please
Love the frozen yogurt and hippie food (juices, vegetarian stuff) at Delishee Yo. Watusi is great for coffee and sandwiches.
Fabulous food at Charlie's Etoile Vert. Somewhat more upscale than most of the vacation restaurants on the island, but we've taken our young kids and had nice dinners.
Porter & Pig is new and has good food and drinks. It's at The Village at Wexford which is less crowded with some nice shopping.