Yes, fine if it's a venue. Iffier if just at your house, but I think it's okay to say many apologies, but you already gave the venue the head count. If it's easy to change, though, I'd just add the extras. (More of an issue if it's a place with a max and you said okay to the siblings because people didn't RSVP on time, so now you would have to axe the siblings to take the late responders.)
That said, we always have a couple of no shows anyway for stuff like that so not sure I'd stress about it. Next time maybe word the deadline even more strongly, letting them know you must know and you can't accommodate late RSVPs.