Yes, in 2009, as a very junior associate in the height of the recession. I made getting a new job my full-time job, and ended up with several offers after about 2 months of looking. I applied to literally hundreds of jobs, and ended up moving across the country (to DC, though my husband had already gotten a sweet but low-paying job here). The single biggest thing is to devote a lot of time to networking. People want to help you. Everyone you know professionally, people you went to school with, people you didn't go to school with. For every job I applied to that I actually wanted, I ran a search on my law school alumni database and reached out to alumni working there to push my resume to the top of the pile. I also reached out within my firm for help, and found that some big name partners were surprisingly willing to make calls for me. Between those two things, I got 3 interviews I probably wouldn't have had otherwise. Try to be patient, as hard as that sounds.
Best of luck.