I don't know anything about Issa's dealings, but real estate is a prime candidate for insider knowledge. You buy land knowing someone wants to build something there, or that a zoning change is in the worKS
WERE IT ONLY SO SIMIPLE AN INNOCUOUS
Read of the Office of Congressional Ethics has to say:
agout a man who's net worth went from 40Mil to >450mil during his role in the HR. A larger gain than anyone in the senate at a period of time when you and I saw our net worth plummet
Wikki
http://en.wikipedia.org/wiki/Office_of_Congressional_Ethics