Anonymous
Post 05/16/2026 00:25     Subject: Aromatase Inhibitors- Your Experience?
Anonymous wrote:Letrozole has been fine.


Everyone is different. Letrozole was terrible for me. Exemestane is better.
Anonymous
Post 05/15/2026 07:44     Subject: Aromatase Inhibitors- Your Experience?
Letrozole has been fine.
Anonymous
Post 05/14/2026 22:03     Subject: Aromatase Inhibitors- Your Experience?
Anyone try Raloxefene? My dr recommended this one as safer for people with retina issues.
Anonymous
Post 05/14/2026 21:44     Subject: Aromatase Inhibitors- Your Experience?
Anonymous wrote:I had a lot of stiffness, that improved dramatically once I started supplementing with vitamin D.


+1. I had a really bad reaction to my first aromatase inhibitor. My vitamin D was around 30 when I went on it without supplementing with D or Calcium. My D dropped to 20 - which is very deficient and had a real negative impact.

I stopped. I took massive doses of vitamin D to quickly get my D up to 60 before trying again The second try (of the same AI) was not a problem. So substantially different

The package insert says to test for Vitamin D levels before starting medications.

Endocrinologists and breast cancer doctors generally recommend in the vitamin D around 40-60 in order to promote bone and prevent cancer.

I test every 2-3 months now - a CMP (which has calcium and alkaline phosphatase), PTH and vitamin D and supplement to maintain proper range for all 3.
Anonymous
Post 05/14/2026 19:37     Subject: Aromatase Inhibitors- Your Experience?
How long are you on it typically
Anonymous
Post 05/14/2026 18:40     Subject: Aromatase Inhibitors- Your Experience?
Anonymous wrote:What about aging? Supposedly you look a lot older bc of the lost estrogen


I was worried about this, but I don’t think it’s made any difference. I also worried about thinning hair and other side effects, but the only thing I’ve noticed is some muscle stiffness after I’ve been sitting a while. Other than that, no issues.
Anonymous
Post 05/14/2026 18:36     Subject: Aromatase Inhibitors- Your Experience?
What about aging? Supposedly you look a lot older bc of the lost estrogen
Anonymous
Post 05/14/2026 08:38     Subject: Aromatase Inhibitors- Your Experience?
NP - which aromatase inhibitor s causing stiffness?
Anonymous
Post 05/13/2026 23:10     Subject: Aromatase Inhibitors- Your Experience?
I had a lot of stiffness, that improved dramatically once I started supplementing with vitamin D.
Anonymous
Post 05/13/2026 23:00     Subject: Aromatase Inhibitors- Your Experience?
r/breastcancer is where you want to go. Tons of personal experiences and well moderated forum.
Anonymous
Post 05/13/2026 22:35     Subject: Re:Aromatase Inhibitors- Your Experience?
I had mild side effects. Some stiffness and hot flashes. Not too bad over all. My attitude was that they were worth trying. Good luck.
Anonymous
Post 05/13/2026 22:19     Subject: Aromatase Inhibitors- Your Experience?
My doctor is suggesting I go on this. I’m interested in hearing personal experiences with this drug.