Yes, you can prune them today.
"Like all panicle hydrangeas, ‘Limelight’ blooms on new wood. ‘Limelight’ hydrangea pruning should take place in late winter or early spring. Remove any dead, broken or diseased branches and cut plants back by a third of their size."
https://www.gardendesign.com/hydrangea/limelight.html
We already have spring blooms happening so the insects will be fine.