When I don't have a ton of prepared questions, I ask the same questions to different people and see how their answers differ.
"Why did you choose this company? What's the most rewarding part of your job?"
I've been on the recruitment end. In my experience, people don't compare notes on the open-ended, non-scripted parts of the interview. So it's not like you'd be busted for asking everyone the same thing.
I am also good at coming up with organic questions based on the discussion. That's important for demonstrating listening skills.