Price is almost the same but the RX 350 is two years older, 67K miles. The NX 300 is newer, 26K miles. All else being equal having a tough time deciding between the two. The RX is a bit bigger, but my kids are older and I don't need the space so much anymore. I do drive cars 10+ years so there's that to figure in. If anyone can offer advice it would be greatly appreciated.