Regarding, "No reputable compounding pharmacy will be providing these at this point in time".

I respectfully disagree. The compounding pharmacy that dispenses my semaglutide script is an independent establishment that has been operating out of the same location since the 1950s. They were very successful for many decades prior to compounding semaglutide and would have had no motive whatsoever to engage in shady practices that would cause damage to their stellar reputation in this community in order to turn a quick profit.

Look on reddit for test groups that are purchasing in bulk buys from overseas. I've lost 60 lbs on tirz I reconstitute myself.

Anonymous wrote:

Anonymous wrote:

Anonymous wrote:Just to be clear, the FDA has said there is no legal basis for the compounding of semaglutide or any of the GLP-1 agonists under patent. Meaning no compounding pharmacy that is providing them is doing so legally. A quick google search will educate you to the risks of using these non-approved drugs from unregulated sources. No reputable compounding pharmacy will be providing these at this point in time. There are a significant number of very shady compounding pharmacies in the country, and the quality of their products typically aligns with the equality of their ethics in these types of cases. FDA has already had adverse event reports from compounded forms of these drugs.

Ditto for drugs from foreign countries. Counterfeit drugs exist in vast quantities and are shipped across borders all the time. Risks are especially high for popular drugs like these. It is highly unlikely that you would be able to distinguish a counterfeit product from an approved product on a visual inspection.

Not to mention new reports of gastroparesis potentially associated with these drugs. You really, really do not want that.

? Gastroparesis is part of what contributes to improved glycemic control and weight loss. It’s a feature, not a bug.

NP. You don't understand. There are degrees to it. A mild version is fine while you lose the weight, but severe versions can kill you. You don't know how you'll react until you are under medication, so be very aware of your symptoms.

I was on it for 3 years and the only side effect I had was losing over 100lbs and stinky egg burps.

I lost 60 lbs on compounded semaglutide. The first 55 of it came off at an average of about 8 lbs per month after which I leveled off and slowly lost an additional 5 lbs which was unintended but okay. 55-60 lbs. got me where I wanted to be, so I started slowly reducing my dosage. No rebound yet but I watch it closely.

Anonymous wrote:

Anonymous wrote:Just to be clear, the FDA has said there is no legal basis for the compounding of semaglutide or any of the GLP-1 agonists under patent. Meaning no compounding pharmacy that is providing them is doing so legally. A quick google search will educate you to the risks of using these non-approved drugs from unregulated sources. No reputable compounding pharmacy will be providing these at this point in time. There are a significant number of very shady compounding pharmacies in the country, and the quality of their products typically aligns with the equality of their ethics in these types of cases. FDA has already had adverse event reports from compounded forms of these drugs.

Ditto for drugs from foreign countries. Counterfeit drugs exist in vast quantities and are shipped across borders all the time. Risks are especially high for popular drugs like these. It is highly unlikely that you would be able to distinguish a counterfeit product from an approved product on a visual inspection.

Not to mention new reports of gastroparesis potentially associated with these drugs. You really, really do not want that.

? Gastroparesis is part of what contributes to improved glycemic control and weight loss. It’s a feature, not a bug.

NP. You don't understand. There are degrees to it. A mild version is fine while you lose the weight, but severe versions can kill you. You don't know how you'll react until you are under medication, so be very aware of your symptoms.

Anonymous wrote:

Anonymous wrote:Just to be clear, the FDA has said there is no legal basis for the compounding of semaglutide or any of the GLP-1 agonists under patent. Meaning no compounding pharmacy that is providing them is doing so legally. A quick google search will educate you to the risks of using these non-approved drugs from unregulated sources. No reputable compounding pharmacy will be providing these at this point in time. There are a significant number of very shady compounding pharmacies in the country, and the quality of their products typically aligns with the equality of their ethics in these types of cases. FDA has already had adverse event reports from compounded forms of these drugs.

Ditto for drugs from foreign countries. Counterfeit drugs exist in vast quantities and are shipped across borders all the time. Risks are especially high for popular drugs like these. It is highly unlikely that you would be able to distinguish a counterfeit product from an approved product on a visual inspection.

Not to mention new reports of gastroparesis potentially associated with these drugs. You really, really do not want that.

? Gastroparesis is part of what contributes to improved glycemic control and weight loss. It’s a feature, not a bug.

Delayed stomach emptying is a feature. Anything more than mild Gastroporeis is a serious medical problem. Ie. Your stomach cannot empty, so you puke.

Anonymous wrote:Just to be clear, the FDA has said there is no legal basis for the compounding of semaglutide or any of the GLP-1 agonists under patent. Meaning no compounding pharmacy that is providing them is doing so legally. A quick google search will educate you to the risks of using these non-approved drugs from unregulated sources. No reputable compounding pharmacy will be providing these at this point in time. There are a significant number of very shady compounding pharmacies in the country, and the quality of their products typically aligns with the equality of their ethics in these types of cases. FDA has already had adverse event reports from compounded forms of these drugs.

Ditto for drugs from foreign countries. Counterfeit drugs exist in vast quantities and are shipped across borders all the time. Risks are especially high for popular drugs like these. It is highly unlikely that you would be able to distinguish a counterfeit product from an approved product on a visual inspection.

Not to mention new reports of gastroparesis potentially associated with these drugs. You really, really do not want that.

? Gastroparesis is part of what contributes to improved glycemic control and weight loss. It’s a feature, not a bug.

Hard pass on illegally compounded products. FDA has issued warnings about adverse reactions and warning Americans not to use them (Google is your friend to confirm and Norvo Nordisc is suing to stop some of the worse offenders.

I am fortunate that my insurance does cover Wegovy— but only because I did a deep dive into their formularies during open season. I’ve lost 32 pounds in about 14 weeks. BUT— I’m being followed by a PA and dietician and am on a 1200 calorie diet with 120 grams of protein a day, 2 hours of strength training a week and 180 minutes of cardio. Also a 50 year old woman.

Even with Wegovy or a safe, legit compound you are going to have to overhaul your current diet, significantly cut your current calories and step up the strength training and exercise to see much weight loss after menopause.

Rybelsus did not work out for me.

I'm 52 and have a lot of weight to lose. I took Rybelsus for a couple of months. The side effects (nausea and diarrhea) were too much for me, and I didn't lose that much weight. YMMV -- hope it works out for you.

Just to be clear, the FDA has said there is no legal basis for the compounding of semaglutide or any of the GLP-1 agonists under patent. Meaning no compounding pharmacy that is providing them is doing so legally. A quick google search will educate you to the risks of using these non-approved drugs from unregulated sources. No reputable compounding pharmacy will be providing these at this point in time. There are a significant number of very shady compounding pharmacies in the country, and the quality of their products typically aligns with the equality of their ethics in these types of cases. FDA has already had adverse event reports from compounded forms of these drugs.

Ditto for drugs from foreign countries. Counterfeit drugs exist in vast quantities and are shipped across borders all the time. Risks are especially high for popular drugs like these. It is highly unlikely that you would be able to distinguish a counterfeit product from an approved product on a visual inspection.

Not to mention new reports of gastroparesis potentially associated with these drugs. You really, really do not want that.

I've been doing research and i found a few clinics

https://www.thewellnessnps.com/semaglutide-subscription

https://ultrabodysculpt.com/weight-loss-injections-cost/

I have been using a compound from my doctors office for 5 months. Lost 28 lbs so far and no issues. It's $550/month.

OP. I am already participating with a weight loss program. But insurance doesn't cover the prescription they gave me. I can't afford $1200/month. Am trying to find out if anyone has had experience with compounded versions, which my weight loss program does in office.

As someone that works in pharmaceuticals, I absolutely would not purchase abroad. There is fake product besides the fact that these are serious drugs. You need proper monitoring and follow up. That said, there are more affordable options. Plenty of places are doing membership programs that including the monitoring and exams here.

This is one: https://www.caraveladmv.com/wegovy-weight-loss-injections-near-me-alexandria-va

Have been prescribed Wegovy for weight loss, but it is not covered by my insurance. Have gone down the many rabbit holes researching options that we've seen on other threads. Before buying a ticket to Mexico to purchase, or waiting for months for a Canadian mail order pharmacy (Rybelsus), I'm wondering if I should try the tirzepatide compound my doctor offered as an alternative.

I would prefer to do Canadian Rybelsus for $250/month than $600/month for tirzepatide compound that isn't regulated or made by Novo Nordisk. However, if I had more anecdotal data regarding the compound, I might be willing to try it. Has anyone had experience with tirzepatide compound locally? I didn't catch the name of the pharmacy they use, but apparently it's in northern Virginia.

Any local firsthand experiences would be appreciated. In other news, it feels pretty surreal to contemplate going to Mexico for a medication. It's not something I would normally consider. But, I'm 50, have hypothyroidism, postmenopausal, am exercising everyday, eating 1500 calories or less each day of healthy fruits, veggies, legumes and still weigh 170. I'm not prediabetic. I'm losing my mind. Something has got to give.