Anonymous wrote:

Anonymous wrote:Maybe your mistake was was taking pax to begin with. It was never tested in vaccinated people. You sound healthy. You honestly probably prolonged your bout with Covid by taking it. My husband was done in 3 days. My kids in 2. Took me 5 personally.

Correct.

Honestly, it might not be. My older teen son had COVID three weeks ago and didn't take Paxlovid. He was pretty sick for a full 5 days and then felt somewhat better but still fatigued. He tested negative for COVID last week and felt better. This weekend, he developed a low-grade fever, sore throat, chills, etc. He is testing negative. Researching it, I found studies saying that between 10 and 30 percent of those with COVID who did not take antivirals experienced a rebound in symptoms. He is still testing negative. Some of the researchers suggested that the rebound could be an immune response, not the virus itself.

Here is a quote:

Smith wasn’t surprised by the results. “As an infectious disease doc, [I] know that respiratory disease viruses often have this waxing and waning,” he says, adding that it also happens with colds, influenza and respiratory syncytial virus (RSV). “It’s just their nature.” This is likely because most symptoms are related to the body’s inflammatory response to the virus, not the virus itself, he says. The inflammation—which is different for everyone—generally lasts longer than the virus, and it ebbs and flows as viral remnants are cleared from the body.

https://www.scientificamerican.com/article/covid-rebound-can-happen-even-without-paxlovid/

Anonymous wrote:Maybe your mistake was was taking pax to begin with. It was never tested in vaccinated people. You sound healthy. You honestly probably prolonged your bout with Covid by taking it. My husband was done in 3 days. My kids in 2. Took me 5 personally.

Correct.

If a drug only staves off symptoms and rebound happens constantly, it’s not a good drug

Does paxlovid mitigate blood clots with Covid?

Maybe your mistake was was taking pax to begin with. It was never tested in vaccinated people. You sound healthy. You honestly probably prolonged your bout with Covid by taking it. My husband was done in 3 days. My kids in 2. Took me 5 personally.

Anonymous wrote:My dr was very clear that rebound means you should consider yourself contagious again so does that mean any positive rapid test you should consider yourself contagious?

ISTR there used to be a thing that once you recovered you might test positive for a while even though you weren’t contagious?

I believe you’re thinking of PCR testing.

Positive means you have enough viral load to be detected, so follow precautions because you can transmit the various hence contagious.

My dr was very clear that rebound means you should consider yourself contagious again so does that mean any positive rapid test you should consider yourself contagious?

ISTR there used to be a thing that once you recovered you might test positive for a while even though you weren’t contagious?

Paxlovid rebound happens. It’s on CDC advisory. Our friend, a pulmonologist, doesn’t really know why. You can test positive again after testing negative.

Anonymous wrote:

Anonymous wrote:The party line/cookbook medicine answer is no second course because “there’s no evidence” rebound is caused by too short a course or will be helped by a longer one. Of course there’s no evidence that those things aren’t true either.

It depends on the doctor.

I considered asking for a second course but the rebound wasn’t too bad, and quickly improved rather than getting worse.

DP. When you had rebound COVID, did you test positive again?

Yes. Tested negative on day 5 of Paxlovid. Had recurrent symptoms and tested positive five days later. Finally tested negative again a little more than a week later.

Anonymous wrote:The party line/cookbook medicine answer is no second course because “there’s no evidence” rebound is caused by too short a course or will be helped by a longer one. Of course there’s no evidence that those things aren’t true either.

It depends on the doctor.

I considered asking for a second course but the rebound wasn’t too bad, and quickly improved rather than getting worse.

DP. When you had rebound COVID, did you test positive again?

The party line/cookbook medicine answer is no second course because “there’s no evidence” rebound is caused by too short a course or will be helped by a longer one. Of course there’s no evidence that those things aren’t true either.

It depends on the doctor.

I considered asking for a second course but the rebound wasn’t too bad, and quickly improved rather than getting worse.

My dad did but he’s mid 70s with some additional risk factors. Also he lives in Texas where they don’t really care.

I was told they only do it once but don’t know why (or even of that’s always true)

Has anyone gotten another dose of Paxlovid? My first time, the symptoms went away almost overnight but now that I've rebounded I feel everything and then some. When getting the first Paxlovid dose, I was told it prevents long Covid - okay - but am I at risk for it now that I'm doing it all over???

Any guidance would be appreciated. I've contacted my doctor but would like to hear what you guys have to say.