Anonymous wrote:MTHFR. Ask to be tested for it. Then you can talk about starting baby aspirin or heparin.

+1 MTHFR is often overlooked in blood panels. Ask to be tested for it specifically. This mutation is fairly common and makes it so body cannot break down folic acid. You can only absorb it as folate or methylfolate. There are various degrees of this mutation. It would absolutely impact you the most the first trimester. I went through 3 years of fertility treatments with no success and no RE of OB bringing it up. In year 4 I saw a functional medicine doctor and she tested for it immediately.

I believe this is the same issue the other poster who can’t remember from 20 years ago posted about.

Anonymous wrote:OP here. No I don't have an RE yet. I have an adult child born when I was much younger. This is a last ditch effort to have another baby. I'm nearly 43. Maybe it's just not happening.

At 43 you should be starting IVF there is very little chance of conceiving a normal embryo with your own eggs.

I'm right there with you OP. Since 36 I've lost 5 pregnancies. The furthest was 14 weeks and the heart stopped beating suddenly. No chromosomal defects identified, all genetic tests came back clear. We're hopefully starting IVF with PDG testing to see how many are normal vs not.

The OB is probably correct in saying chromosomal abnormalities, but have you had the products of conception tested each time to confirm that? We conceived easily by IUI but the 2 pregnancies I had by IUI at 41 were both anuploid. We did two rounds of IVF at age 42. Only 3 eggs, turned into 2 blasts round 1, both abnormal. Switched clinics, 10 eggs, had 4 blasts tested, 1 normal. Will be delivering within a few weeks at age 43.
It's true age is not on your side, but accept no explanations without data to support them.

OP here. No I don't have an RE yet. I have an adult child born when I was much younger. This is a last ditch effort to have another baby. I'm nearly 43. Maybe it's just not happening.

Anonymous wrote:OP here.

My OB just says it’s chromosomal abnormalities and my age. I haven’t done the panel PP asks about. I am hypothyroid but my TSH is checked often. As soon as I know I’m pregnant, I increase my Synthroid dose.

What does the baby aspirin do?

What does your RE say? You are wasting time with your OB. If s/he hasn't told you this, it is criminal.

It's been 20 years and I wish I can remember what the issue I had was called. I had the same problem. It ended up being I lack a protein that helps me absorb folic acid. My doctor made me take B, vitamin and folic acid supplements the entire pregnancy on top of my prenatal vitamins. I was finally able to carry to term and I have two children. My sister had a similar issue, but she was missing more than one protein and they had to give her shots throughout her pregnancy.

What is your specific age? This is not an OB’s area of expertise unless testing indicates chromosomal issues after a D & C. They don’t know if your blood is clotting too much, if your blood sugar levels are ideal, if you could benefit from a thicker lining, etc. You need an RE if you want to get pregnant and stay pregnant after, say, 42. If only to collect data. Ask if there is any harm in being more aggressive about your TSH pre-conception. I would also try some anti inflammatory protocols, increase sun exposure and activity.

MTHFR. Ask to be tested for it. Then you can talk about starting baby aspirin or heparin.

OP here.

My OB just says it’s chromosomal abnormalities and my age. I haven’t done the panel PP asks about. I am hypothyroid but my TSH is checked often. As soon as I know I’m pregnant, I increase my Synthroid dose.

What does the baby aspirin do?

Have you done a recurrent pregnancy loss panel? Baby aspirin? Check for insulin resistance , hypothyroid, blood clotting etc.

I'm sorry, OP. What does your doctor say? People on the internet cannot answer this question for you, as much you want them to say it's your age.

Sorry OP. That is tough

Probably at 40. Do you have other kids?

Early 40s.
Apparently I have no problems getting pregnant, but I lose fetuses at 7-8 weeks - they never develop heartbeats.
I'd appreciate your insight as to what this might be and what I can do.